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151 - 200 of 7144 citations for 1 Bromo 3 difluoromethoxy benzene since 2020

• HIV-1 controllers possess a unique CD8+ T-cell activation phenotype and loss of control is associated with increased expression of exhaustion markers

  Amber D Jones, et al., bioRxiv - Immunology 2024

  Quote: ... and/or anti-Tim-3 (CD366) antibody (BioLegend, UltraLEAF purified anti-human ...
• PD-1 blockade enhances HIV-1 vaccine-induced CD8⁺ T-cell responses in PWH early ART-treated

  Miguel Marin, et al., bioRxiv - Immunology 2024

  Quote: ... and TIM-3 (PE, clone F38-2E2, Biolegend) antibodies for 25 minutes ...
• Divergent response to radio-immunotherapy is defined by intrinsic features of the tumor microenvironment

  Jacob Gadwa, et al., bioRxiv - Immunology 2024

  Quote: ... GATA-3: Alexa Fluor 647 (Clone: 16E10A23, Biolegend). Samples were analyzed on a Cytek Aurora spectral cytometer (Cytek Biosciences) ...
• Wound microbiota-mediated correction of matrix metalloproteinase expression promotes re-epithelialization of diabetic wounds

  Ellen K. White, et al., bioRxiv - Microbiology 2023

  Quote: ... Tissue was rinsed 3 times in 1X PBS and then incubated with 1:5000 dilution rabbit polyclonal anti-Keratin-14 antibody (Biolegend, Clone Poly19053) for 1 hour and then detected with 1:10000 dilution goat anti-Rabbit IgG Secondary Antibody conjugated with Alexa Fluor™ 488 (ThermoFisher Scientific ...
• KLRG1 marks tumor-infiltrating CD4 T cell subsets associated with tumor progression and immunotherapy response

  Casey R. Ager, et al., bioRxiv - Immunology 2023

  Quote: ... then were resuspended in FACS (PBS + 3% FBS + 1mM EDTA + 10mM HEPES) supplemented with TruStain FcX (1:50; BioLegend; San Diego, CA) and TruStain Monocyte Blocker (1:20 ...
• Catabolism of extracellular glutathione supplies amino acids to support tumor growth

  Fabio Hecht, et al., bioRxiv - Cancer Biology 2024

  Quote: ... the pellets were incubated for 1 hour in 60 µL of staining solution (1% BSA and 0.5% Tween-20 in PBS) containing 3 µL of anti-BrdU-FITC monoclonal antibody (Biolegend 364104, clone 3D4). The samples were subsequently washed with 1 mL of 1% BSA and 0.5% Tween-20 in PBS ...
• Natural killer-like B cells promote Th17 cell differentiation and exacerbate rheumatoid arthritis

  Ping Wang, et al., bioRxiv - Immunology 2021

  Quote: ... anti-CD28 and anti-CD40 (3 μg/mL, Biolegend) in a round-bottom 96-well plate ...
• High Frequencies of PD-1⁺TIM3⁺TIGIT⁺CTLA4⁺ Functionally Exhausted SARS-CoV-2-Specific CD4⁺ and CD8⁺ T Cells Associated with Severe Disease in Critically ill COVID-19 Patients

  Pierre-Gregoire Coulon, et al., bioRxiv - Immunology 2022

  Quote: ... anti-TIM-3 (BV 711, clone F38-2E2 – BioLegend), anti-PD1 (PE-Cy7 ...
• Systematically optimized BCMA/CS1 bispecific CAR-T cells robustly control heterogeneous multiple myeloma

  Eugenia Zah, et al., bioRxiv - Bioengineering 2020

  Quote: ... LAG-3 (eBioscience #17-2239-42 or BioLegend #369314), CD8 (Miltenyi #130-113-164) ...
• SARS-CoV-2-associated ssRNAs activate inflammation and immunity via TLR7/8

  Valentina Salvi, et al., bioRxiv - Immunology 2021

  Quote: ... FITC-conjugated anti-mouse CD40 (clone HM40-3, Biolegend) and APC-CY7-conjugated anti-mouse CD86 (clone GL-1 ...
• Vaccinia E5 is a major inhibitor of the DNA sensor cGAS

  Ning Yang, et al., bioRxiv - Microbiology 2021

  Quote: ... and stained with antibodies against CD40 (3/23, Biolegend) and CD86 (GL-1 ...
• Sperm-specific COX6B2 enhances oxidative phosphorylation, proliferation, and survival in lung adenocarcinoma

  Chun-Chun Cheng, et al., bioRxiv - Cancer Biology 2020

  Quote: ... with 3 μl of Annexin-V-APC (640941, BioLegend) and DAPI (200 ng/ml) ...
• Circulating levels of epirubicin cause endothelial senescence while compromising metabolic activity and vascular function

  Amanda J Eakin, et al., bioRxiv - Cell Biology 2020

  Quote: ... rat anti-mouse Mac-2 (Galectin-3, 125402, Biolegend) for myeloid cells (Ho and Springer 1982) ...
• Systematic prioritization of candidate genes in disease loci identifies TRAFD1 as a master regulator of IFNγ signalling in celiac disease

  Adriaan van der Graaf, et al., bioRxiv - Genetics 2020

  Quote: ... or IL-21 (3 ng/ml, Biolegend, cat 571204) (n=8 samples per condition ...
• MiR-324-5p regulates the structure of dendritic spines and is essential for hippocampal long-term potentiation

  Emma V Parkins, et al., bioRxiv - Neuroscience 2023

  Quote: ... Beta 3 tubulin rabbit polyclonal (BioLegend Cat# 802001, RRID:AB_2564645), Anti-PSD-95 MAGUK scaffold protein mouse monoclonal (Antibodies Incorporated Cat# 75-348 ...
• FGF21 deletion mildly exacerbates hepatic dysfunction in MASH diet and alcohol fed rats

  Peter Aldiss, et al., bioRxiv - Physiology 2024

  Quote: ... anti-galectin-3 (cat. 125402, Biolegend, San Diego, CA), alpha-smooth muscle action (α-SMA ...
• PP2A catalytic subunit alpha is critically required for CD8⁺ T cell homeostasis and anti-bacterial responses

  Xian Zhou, et al., bioRxiv - Immunology 2024

  Quote: ... Alexa fluor 700-labeled anti-CD8β (Lyt-3; Biolegend), BV650-labeled anti-CD45.1 (Ly5.1 ...
• A Broad-Spectrum Multi-Antigen mRNA/LNP-Based Pan-Coronavirus Vaccine Induced Potent Cross-Protective Immunity Against Infection and Disease Caused by Highly Pathogenic and Heavily Spike-Mutated SARS-CoV-2 Variants of Concern in the Syrian Hamster Model

  Swayam Prakash, et al., bioRxiv - Immunology 2024

  Quote: ... anti-TIM-3 (BV 711, clone F38-2E2 – BioLegend), anti-PD1 (PE-Cy7 ...
• Early-stage idiopathic pulmonary fibrosis is characterized by bronchoalveolar accumulation of SPP1⁺ macrophages

  Jiangyan Yu, et al., bioRxiv - Immunology 2023

  Quote: ... Then cells were stained with CCR7 (3:100, BioLegend) and CADM1 (2:100 ...
• A microbiota-derived metabolite instructs peripheral efferocytosis

  Pedro H. V. Saavedra, et al., bioRxiv - Immunology 2022

  Quote: ... and 3 μg/ml recombinant annexin V (BioLegend, 640901) for 1 hour at 4 °C ...
• Type 1 interferon remodels normal and neoplastic hematopoiesis in human

  Chhiring Lama, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 2 or 3 (TotalSeq-A, clone LNH-94, Biolegend) for GoT-IM ...
• Coopting T cell proximal signaling molecules enables Boolean logic-gated CAR T cell control

  Aidan M. Tousley, et al., bioRxiv - Synthetic Biology 2022

  Quote: ... TIM-3 (BV510 or BV650, Clone F38-2E2, BioLegend), LAG-3 (PE ...
• Human effector CD8⁺ T cells with an exhausted-like phenotype control tumor growth in vivo in a humanized tumor model

  Juliane Mietz, et al., bioRxiv - Immunology 2024

  Quote: ... Galectin-9-PE-Cy7 (Biolegend, 9M1-3, Cat. 348916), TIGIT-APC-Cy7 (Biolegend ...
• LAG-3 blockade reactivates the CD8⁺ T cell expansion program to re-expand contracted clones in the tumor

  Munetomo Takahashi, et al., bioRxiv - Immunology 2024

  Quote: ... and anti-LAG-3 (clone C9B7W, BioLegend or Selleck) was injected intraperitoneally at a dose of 200 μg per mouse on days 14 and 16 (for bulk RNA-seq data ...
• Broad-spectrum RNA antiviral inspired by ISG15^-/- deficiency

  Yemsratch T. Akalu, et al., bioRxiv - Immunology 2024

  Quote: ... or with anti-cleaved caspase-3 antibody (Biolegend 559341) for quantification by flow cytometry.
• Cancer-associated adipocytes mediate CD8⁺T cell dysfunction via FGF21-driven lipolysis

  Sumiya Dalangood, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-TIM-3-PE/Cy7 (cat#134009, CloneB8.2C12, Biolegend), anti-LAG3-Percp/Cyanine5.5 (cat#125211 ...
• Catabolism of extracellular glutathione supplies amino acids to support tumor growth

  Fabio Hecht, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and 3 µL of Annexin V-FITC (Biolegend 0640906). Then ...
• Polyglutamylation of microtubules drives neuronal remodeling

  Antoneta Gavoci, et al., bioRxiv - Cell Biology 2024

  Quote: ... The following primary antibodies were used in this study: anti-tubulin beta-3 conjugated to Alexa Fluor 488 (BioLegend; AB_2562669; mouse IgG2a, 1:200), Alexa Fluor 555 (BD PharMingen ...
• Targeting tumour-intrinsic neural vulnerabilities of glioblastoma

  Sohyon Lee, et al., bioRxiv - Cancer Biology 2023

  Quote: Other conjugated antibodies used in this study include the following: Alexa Fluor® 647 anti-Tubulin Beta 3 (1:1000, Biolegend, #657406, clone AA10), Alexa Fluor® 488 anti-Vimentin (1:500 ...
• BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection

  Yunlong Cao, et al., bioRxiv - Immunology 2022

  Quote: ... 3 μL PE/Cyanine7 anti-human IgM antibody (BioLegend, 314532), 0.0052 μg biotinylated Ovalbumin (SinoBiological ...
• CAR-NK Cells Effectively Target the D614 and G614 SARS-CoV-2-infected Cells

  Minh Ma, et al., bioRxiv - Immunology 2021

  Quote: ... FITC anti-human CD223 (LAG-3) antibody (clone 11C3C65, BioLegend), BV510 anti-human CD314 (NKG2D ...
• FACT is recruited to the +1 nucleosome of transcribed genes and spreads in a Chd1-dependent manner

  Célia Jeronimo, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-Rpb3 (Neoclone W0012, 3 μL; BioLegend 665004, 1.5 μL), anti-Flag (Sigma-Aldrich F3165 ...
• Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T cells

  Tomokazu S. Sumida, et al., bioRxiv - Immunology 2020

  Quote: ... The following antibodies were used: anti-LAG-3 (11C3C65, BioLegend), anti-PD-1 (EH12.1 ...
• Efficacy of Targeting SARS-CoV-2 by CAR-NK Cells

  Minh Ma, Saiaditya Badeti, Ke Geng, Dongfang Liu, bioRxiv - Immunology 2020

  Quote: ... FITC anti-human CD223 (LAG-3) antibody (clone 11C3C65, BioLegend), BV510 anti-human CD314 (NKG2D ...
• Profound Treg perturbations correlate with COVID-19 severity

  Silvia Galván-Peña, et al., bioRxiv - Immunology 2020

  Quote: ... CD127 AF488 (clone A019D5, BioLegend, cat# 351314, dilution 3:100); CD25 PE-Cy7 (clone BC96 ...
• CD8+ T cell epitope variations suggest a potential antigen presentation deficiency for spike protein of SARS-CoV-2

  Congling Qiu, et al., bioRxiv - Immunology 2021

  Quote: ... washed for 3 times with Washing Buffer (BioLegend Cat#421601) and blocked with Dilution Buffer (0.5M Tris pH 8.0 ...
• Cell-Intrinsic and Extrinsic Effects of Galectin-1 and Galectin-3 in B-Cell Precursor Acute Lymphoblastic Leukemia

  Fei Fei, et al., bioRxiv - Cancer Biology 2021

  Quote: ... cells were incubated with PE-Galectin-3 (Biolegend cat# 126706) or matched isotype control for 15 mins and analyzed on BD Accuri C6 cytometer (BD Biosciences ...
• Tissue-resident regulatory T cells exert dualistic anti-tumour and pro-repair function in the exocrine pancreas

  Julie Stockis, et al., bioRxiv - Immunology 2024

  Quote: ... injection of 3 µg anti-CD45.2-PE (clone 104, Biolegend) antibody 3 min prior to sacrifice ...
• Early infection response of the first trimester human placenta at single-cell scale

  Regina Hoo, et al., bioRxiv - Genomics 2023

  Quote: ... TotalSeq™-B0253 anti-human Hashtag 3 Antibody (394635, Biolegend), TotalSeq™-B0254 anti-human Hashtag 4 Antibody (394637 ...
• Targeting CXCR4 with [²¹²Pb/²⁰³Pb]-Pentixather Significantly Increases Overall Survival in Small Cell Lung Cancer

  Keegan A. Christensen, et al., bioRxiv - Cancer Biology 2024

  Quote: ... 3×106 cells were stained with Zombie Aqua (423102, BioLegend) for 20 min at room temperature for live/dead cells discrimination ...
• Gene-corrected Parkinson’s disease neurons show the A30P alpha-synuclein point mutation leads to reduced neuronal branching and function

  Peter A. Barbuti, et al., bioRxiv - Neuroscience 2020

  Quote: ... the neurons were fixed and stained as previously described38 using primary antibodies for β-3-Tubulin (TUJ1; 1:200; BioLegend, San Diego, CA, USA; 801201) and TH (1:300 ...
• Prostacyclin as a Negative Regulator of Angiogenesis in the Neurovasculature

  Tasha R Womack, et al., bioRxiv - Neuroscience 2021

  Quote: ... Rat antibody against Notch 3 intracellular domain was obtained from Biolegend. Blots were probed with a mouse anti-actin (ThermoFisher ...
• Intracellular sterol sensing controls intestinal B cell differentiation

  Bruno C. Trindade, et al., bioRxiv - Immunology 2021

  Quote: ... Color development was stopped with 3 M H2SO4 stop solution (Biolegend). Purified mouse IgA (Southern Biotech ...
• The Ebola virus matrix protein clusters phosphatidylserine, a critical step in viral budding

  Monica L. Husby, et al., bioRxiv - Microbiology 2022

  Quote: ... Cells were blocked with 3% BSA/PBS cell staining buffer (BioLegend) and incubated at 37°C for 2 hours ...
• The challenge of distinguishing cell-cell complexes from singlet cells in non-imaging flow cytometry and single-cell sorting

  Julie G Burel, et al., bioRxiv - Immunology 2020

  Quote: ... 3 μl of anti-human CD3-AF700 antibody (clone UCHT1, Biolegend) and 1 μl of anti-human CD14-PE antibody (clone 61D3 ...
• Mitochondrial respiration contributes to the interferon gamma response in antigen presenting cells

  Michael C. Kiritsy, et al., bioRxiv - Immunology 2020

  Quote: ... CD40 (APC anti-mouse CD40 Antibody, Clone 3/23 Biolegend 124611), or PD-L1 (APC anti-mouse CD274 (B7-H1 ...
• Profound Treg perturbations correlate with COVID-19 severity

  Silvia Galván-Peña, et al., bioRxiv - Immunology 2020

  Quote: ... CD25 PE-Cy7 (clone BC96, BioLegend, cat# 302611, dilution 3:100); KLRG1 APC-Cy7 (clone 2FI/KLRG1 ...
• A minimal-complexity light-sheet microscope maps network activity in 3D neuronal systems

  Paulina M Wysmolek, et al., bioRxiv - Neuroscience 2022

  Quote: ... and anti-Tubulin ß 3 antibody (Clone Tuj1, BioLegend, MMS-435P) respectively.
• Inhibition of Acyl-CoA Synthetase Long Chain Isozymes Decreases Multiple Myeloma Cell Proliferation and Causes Mitochondrial Dysfunction

  Connor S. Murphy, et al., bioRxiv - Cancer Biology 2024

  Quote: ... washed 3 times with Cell Staining Buffer (BioLegend, Cat. No. 420201) and stained with APC-Annexin V (1:20 ...
• ZEB2 regulates the development of CD11c+ atypical B cells

  Xin Gao, et al., bioRxiv - Immunology 2022

  Quote: ... in the presence of 3 μg/ml anti-CD40 antibody (Biolegend) w/wo 50 ng/mL IL-21 ...