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451 - 500 of 2032 citations for 3 4 Ethoxy 3 methoxy phenyl 3 thiophene 2 carbonyl amino propionic acid since 2020

• Acute lymph node slices are a functional model system to study immunity ex vivo

  Maura C. Belanger, et al., bioRxiv - Immunology 2020

  Quote: ... IL-4 (ELISA MAX standard, Biolegend) and TNFα (R&D Systems ...
• Lyophilized mRNA-lipid nanoparticle vaccines with long-term stability and high antigenicity against SARS-CoV-2

  Liangxia Ai, et al., bioRxiv - Immunology 2022

  Quote: ... IL-4 PE (Biolegend, cat.504104), and IL-5 APC (Biolegend ...
• Melanoma-intrinsic NR2F6 activity regulates anti-tumor immunity

  Hyungsoo Kim, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and V5-tag (7/4, Biolegend).
• PPAR-γ regulates the effector function of human T_H9 cells by promoting glycolysis

  Nicole L. Bertschi, et al., bioRxiv - Immunology 2022

  Quote: ... IL-4 (50 ng/ml) (BioLegend) for TH2 cells ...
• Human cerebrospinal fluid single exosomes in Parkinson’s and Alzheimer’s diseases

  Koya Yakabi, et al., bioRxiv - Neuroscience 2023

  Quote: ... Aquaporin-4 (E5206) (BioLegend catalog #600352), CD11b (M1/70 ...
• A single-dose MCMV-based vaccine elicits long-lasting immune protection in mice against distinct SARS-CoV-2 variants

  Kristin Metzdorf, et al., bioRxiv - Immunology 2024

  Quote: ... CD11a (M17/4, BioLegend, CA, USA), CD62L (MEL-14 ...
• CTLA-4 tail fusion enhances CAR-T anti-tumor immunity

  Xiaoyu Zhou, et al., bioRxiv - Immunology 2023

  Quote: ... or anti-CTLA-4 antibody (Biolegend) at 37°C for 1 hour ...
• Selective Inhibition of Interleukin-2 Inducible T Cell Kinase (ITK) Enhances Anti-Tumor Immunity in Association with Th1-skewing, Cytotoxic T cell Activation, and Reduced T Cell Exhaustion

  Lih-Yun Hsu, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-human IL-4 (OA19A66, Biolegend) and anti-human IL-5 (TRFK5 ...
• Diet Induced Obesity and Diabetes Enhance Mortality and Reduces Vaccine Efficacy for SARS-CoV-2

  Robert M Johnson, et al., bioRxiv - Microbiology 2023

  Quote: ... IL-4 BV605 (BioLegend, clone: 11B11), and IL-17a BV711 (BioLegend ...
• Soquelitinib, A Selective Inhibitor of Interleukin-2-Inducible T Cell Kinase (ITK), is Active in Several Murine Models of T Cell-Mediated Inflammatory Disease

  Lih-Yun Hsu, et al., bioRxiv - Immunology 2023

  Quote: ... anti-mouse IL-4 (11B11, Biolegend) and anti-mouse IFNγ (XMG1.2 ...
• Membrane positioning across antigen-induced synaptic contacts tunes CAR-T cell signaling and effector responses

  Fenglei Li, Kaushik Choudhuri, bioRxiv - Immunology 2023

  Quote: ... with 100ng/ml hIL-4 (Biolegend) 2days post transduction ...
• Limiting mitochondrial-derived ATP transfer to the cytosol enhances T-cell activation

  Omri Yosef, et al., bioRxiv - Immunology 2024

  Quote: ... and IL-4 (Biolegend, BLG-431104) cytokines using enzyme-linked immunosorbent assay (ELISA).
• Initial TCR Signal Strength Imprints GATA3 and Tbet Expression Driving T-helper Cell Fate Decisions

  Mohammad Ameen Al-Aghbar, et al., bioRxiv - Immunology 2024

  Quote: ... PE/Cy7-IL-4 (11B11, Biolegend), PerCP-Cy5.5-IFNγ (XMGL2 ...
• IL-1β Signalling Modulates T Follicular Helper and Regulatory Cells in Human Lymphoid Tissues

  Romain Vaineau, et al., bioRxiv - Immunology 2024

  Quote: ... CTLA-4 (BV605, 1/40, BioLegend), PD-1 (PE-Cy5.5 ...
• Clustered macrophages cooperate to eliminate tumors via coordinated intrudopodia

  Lawrence J. Dooling, et al., bioRxiv - Bioengineering 2024

  Quote: ... or interleukin-4 (IL4, BioLegend 574302) to polarize to M1 and M2 states ...
• Senescence rewires microenvironment sensing to facilitate anti-tumor immunity

  Hsuan-An Chen, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and cultured in presence of IL-2 (2 ng/ml; Biolegend), IL-7 (2.5 ng/ml ...
• Methylmalonic acid induces metabolic abnormalities and exhaustion in CD8⁺ T cells to suppress anti-tumor immunity

  Joanne D. Tejero, et al., bioRxiv - Immunology 2024

  Quote: ... and 10 ng/mL recombinant mouse interleukin-2 (IL-2) (BioLegend); additionally ...
• Enhancing and inhibitory motifs have coevolved to regulate CD4 activity

  Mark S. Lee, et al., bioRxiv - Immunology 2021

  Quote: ... were coated overnight at 4°C with 8µg of biotinylated anti-CD4 antibody (clone RM4-4, BioLegend). Prior to immunoprecipitation (IP) ...
• Proteomics reveals unique identities of human TGF-β-induced and thymus-derived CD4⁺ regulatory T cells

  Mark Mensink, et al., bioRxiv - Immunology 2022

  Quote: ... Cell surface expression of CTLA-4 was measured by adding anti-CTLA-4-PE-Dazzle594 mAb (BioLegend) in culture during restimulation for 24 h ...
• The CD4 transmembrane GGXXG and juxtamembrane (C/F)CV+C motifs mediate pMHCII-specific signaling independently of CD4-LCK interactions

  Mark S. Lee, et al., bioRxiv - Immunology 2023

  Quote: ... were coated overnight at 4°C with 8μg of biotinylated anti-CD4 antibody (clone RM4-4, BioLegend). Prior to immunoprecipitation (IP) ...
• Single cell profiling of T and B cell repertoires following SARS-CoV-2 mRNA vaccine

  Suhas Sureshchandra, et al., bioRxiv - Immunology 2021

  Quote: ... IgD (IA6-2, BioLegend), CD27 (M-T271 ...
• Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells

  Dehao Huang, et al., bioRxiv - Immunology 2021

  Quote: ... TRAIL (Biolegend, RIK-2), FasL (Biolegend ...
• The NK receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells

  Sumit Sen Santara, et al., bioRxiv - Immunology 2021

  Quote: ... 2 μM monensin (BioLegend) and 3 μM brefeldin A (BD ...
• The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation

  Danielle Minns, et al., bioRxiv - Immunology 2020

  Quote: ... IL-2 (Biolegend, #431004) and IL-22 (Biolegend ...
• Systemic and mucosal mobilization of granulocyte subsets during lentivirus infection

  Rhianna Jones, et al., bioRxiv - Immunology 2021

  Quote: ... CD32 (FUN-2; BioLegend), CD95 (DX2 ...
• Regeneration of humoral immunity from pluripotent stem cells by defined transcription factors

  Qi Zhang, et al., bioRxiv - Immunology 2021

  Quote: ... CD138(281-2, BioLegend), CD38(90 ...
• Deep immune profiling of the maternal-fetal interface with mild SARS-CoV-2 infection

  Suhas Sureshchandra, et al., bioRxiv - Immunology 2021

  Quote: ... IgD (IA6-2, BioLegend), CD27 (M-T271 ...
• Circulating mast cell progenitors migrate to atopic dermatitis-like skin then adapt locally

  Yuki Honda Keith, et al., bioRxiv - Immunology 2022

  Quote: ... integrinβ2 (M18/2; BioLegend), IgE (R35-72 ...
• Integration of Avidity and Differentiation is enabled by CD8⁺ T-cell sensing of IFN-γ

  Lion F.K. Uhl, et al., bioRxiv - Immunology 2023

  Quote: ... IL-2 (Biolegend, #575404), IL-1β (Biolegend ...
• Type I interferon dynamics determines memory B cell epigenetic identity in chronic viral infection

  Lucy Cooper, et al., bioRxiv - Immunology 2023

  Quote: ... or 2 (Biolegend #155863) for 20 minutes at 4°C ...
• Novel Fas-TNFR chimeras that prevents Fas ligand-mediated kill and signals synergistically to enhance CAR T-cell efficacy

  Callum McKenzie, et al., bioRxiv - Synthetic Biology 2023

  Quote: ... IL-2 (Biolegend; 431804), CCL1 (R&D Systems ...
• Manufacturing CD20/CD19-targeted iCasp9 regulatable CAR-T_SCM cells using qCART, the Quantum pBac-based CAR-T system

  Peter S. Chang, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and IL-2 (BioLegend) were quantified by ELISA according to manufacturer’s instructions.
• Acquired resistance to PD-L1 inhibition is associated with an enhanced type I IFN-stimulated secretory program in tumor cells

  Yuhao Shi, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD8b.2 (Biolegend, 140416), Granzyme B (Biolegend ...
• Lung Microbiome Intervention Attenuates Herpesvirus-Induced Post-HCT Pulmonary Fibrosis Through PD-L1 Upregulation on Dendritic Cells

  Joshua B. Perkins, et al., bioRxiv - Immunology 2024

  Quote: ... CD8a (Ly-2, BioLegend), and CCR6 (29-2L17 ...
• Impaired complement regulation drives chronic lung allograft dysfunction after lung transplantation

  Hrishikesh S. Kulkarni, et al., bioRxiv - Immunology 2024

  Quote: ... CD138 (281-2; Biolegend) CD38 (S21016F ...
• Macrophage-Based iNos Reporter Reveals Polarization and Reprogramming in the Context of Breast Cancer

  Javier A. Mas-Rosario, et al., bioRxiv - Immunology 2022

  Quote: ... culture media was removed and replaced with media containing either 50 ng/mL interleukin 4 (IL-4) (BioLegend) for 48 hr to generate M2 macrophages or 50 ng/mL interferon-gamma (IFN-γ ...
• Soluble CTLA-4 raises the threshold for T-cell activation and modulates anti-tumour immunity

  Paul T. Kennedy, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and supplemented with sCTLA-4 conditioned media or murine CTLA-4-Fc fusion protein (10 µg/mL, BioLegend). After 4 days ...
• Progenitor identification and SARS-CoV-2 infection in long-term human distal lung organoid cultures

  Ameen A. Salahudeen, et al., bioRxiv - Cell Biology 2020

  Quote: ... Mouse anti-TNFRSF12A (clone ITEM-4, Biolegend) was utilized for (Fig ...
• Synergistic activity of Nanog, Pou5f3, and Sox19b establishes chromatin accessibility and developmental competence in a context-dependent manner

  Liyun Miao, et al., bioRxiv - Developmental Biology 2020

  Quote: ... 4 µg of anti-RNA polymerase II CTD repeat YSPTSPS antibody [8WG16] from Abcam (ab817) and 4 µg from BioLegend (664912) were used for each sample ...
• Antigen-derived peptides directly engage the unfolded-protein sensor IRE1α to curb cross-presentation by dendritic cells

  Ofer Guttman, et al., bioRxiv - Cell Biology 2021

  Quote: ... and 10 ng/ml IL-4 (Biolegend) for 9 days ...
• Suppression of Cytotoxic T Cell Functions and Decreased Levels of Tissue Resident Memory T cell During H5N1 infection

  Matheswaran Kandasamy, et al., bioRxiv - Microbiology 2020

  Quote: ... anti-CD4 (2µg/ml, RM4-4; Biolegend), anti-CD3 (2µg/ml ...
• High Frequencies of PD-1⁺TIM3⁺TIGIT⁺CTLA4⁺ Functionally Exhausted SARS-CoV-2-Specific CD4⁺ and CD8⁺ T Cells Associated with Severe Disease in Critically ill COVID-19 Patients

  Pierre-Gregoire Coulon, et al., bioRxiv - Immunology 2022

  Quote: ... anti-CTLA-4 (APC, clone BNI3 – BioLegend), anti-CD138 (APC-Cy-7 ...
• Heterotypic Influenza Infections Mitigate Susceptibility to Secondary Bacterial Infection

  Ellyse M. Cipolla, et al., bioRxiv - Immunology 2022

  Quote: ... Cd11a (M17/4,BioLegend, San Diego, CA), Cd127 (SB/199,Invitrogen-ThermoFisher Scientific ...
• Vaccine Elicitation of HIV Broadly Neutralizing Antibodies from Engineered B cells

  Deli Huang, et al., bioRxiv - Immunology 2020

  Quote: ... IL-4 at 50ng/ml(Biolegend, #574306), anti-CD40 at 5 μg/ml (Thermo ...
• Programming the lymph node immune response with Amphiphile-CpG induces potent cellular and humoral immunity following COVID-19 subunit vaccination in mice and non-human primates

  Lochana M. Seenappa, et al., bioRxiv - Immunology 2022

  Quote: ... IL-4 (PE, clone: 8D4-8, BioLegend), TNFα (BV605 ...
• Differential Nr4a1 and Nr4a3 expression discriminates tonic from activated TCR signalling events in vivo

  Emma Jennings, et al., bioRxiv - Immunology 2020

  Quote: ... TCRVβ5.1/5.2 APC (Clone MR9-4, BioLegend), B220 PerCPcy5.5 (Clone RA3-6B2 ...
• Coordinated changes in glycosylation regulate the germinal centre through CD22

  Jhon R. Enterina, et al., bioRxiv - Immunology 2021

  Quote: ... Mouse IL-4 (1 ng/mL; BioLegend) was added to primary co-culture for 4 days ...
• Acute lymph node slices are a functional model system to study immunity ex vivo

  Maura C. Belanger, et al., bioRxiv - Immunology 2020

  Quote: ... ELISA MAX detection anti-IL-4 (Biolegend), or detection TNFα (R&D Systems ...
• Antigen and Checkpoint Receptor Recalibration of T Cell Receptor Signal Strength

  Thomas A.E. Elliot, et al., bioRxiv - Immunology 2021

  Quote: ... CTLA-4 PE (clone UC10-4B9, BioLegend), OX40 APC (clone OX-86 ...
• The PD-1 checkpoint receptor maintains tolerance of self-reactive CD8 T cell in skin

  Martina Damo, et al., bioRxiv - Immunology 2021

  Quote: ... CD4 (clone GK1.5 or RM4-4, BioLegend), CD44 (clone IM7 ...