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501 - 550 of 2898 citations for 1 4 Nitrophenyl cyclobutanecarbonitrile since 2020

• Multi-parametric analysis of 58 SYNGAP1 variants reveal impacts on GTPase signaling, localization and protein stability

  Fabian Meili, et al., bioRxiv - Genetics 2020

  Quote: ... 1:50 (R&D Systems, IC25062V), (2 ...
• Biomimetic sponges improve muscle structure and function following volumetric muscle loss

  Gabriel Haas, et al., bioRxiv - Bioengineering 2020

  Quote: ... CD31 (1:100; R&D systems), α-bungarotoxin (1:100 ...
• Neprilysin-sensitive amyloidogenic Aβ versus IDE-sensitive soluble Aβ: a probable mechanistic cause for sporadic Alzheimer’s disease

  Hiroki Sasaguri, et al., bioRxiv - Neuroscience 2021

  Quote: ... NEP (1:500, R&D Systems), IDE (1:1,000 ...
• Single cell trajectory analysis of human pluripotent stem cells differentiating towards lung and hepatocyte progenitors

  Chaido Ori, et al., bioRxiv - Developmental Biology 2021

  Quote: ... 1 μM CHIR99021 (R&D Systems) and 0.25mM (day 1 ...
• SLIT2-ROBO signaling in tumor-associated microglia/macrophages drives glioblastoma immunosuppression and vascular dysmorphia

  Luiz Henrique Geraldo, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Robo2 (R&D Systems, 1:500), Actin (Sigma ...
• Suppressor of Fused regulation of Hedgehog Signaling is Required for Proper Astrocyte Differentiation

  Danielle M. Spice, et al., bioRxiv - Developmental Biology 2022

  Quote: ... GLI3 (1:1000; R&D Systems), SUFU (1:1000 ...
• CTLA-4 regulates PD-L1-PD-1 interactions via transendocytosis of CD80

  Alan Kennedy, et al., bioRxiv - Immunology 2022

  Quote: ... PD-1 Ig (R&D Systems), CTLA-4 Ig (Abatacept ...
• A Microengineered Brain-Chip to Model Neuroinflammation in Humans

  I. Pediaditakis, et al., bioRxiv - Bioengineering 2022

  Quote: ... ICAM-1 (R&D Systems; BBA3), Ki67 (Abcam ...
• Cbln1 regulates axon growth and guidance in multiple neural regions

  Peng Han, et al., bioRxiv - Neuroscience 2021

  Quote: ... Tag1 (1:200, R&D Systems), NFM (1:1000 ...
• Cbln1 regulates axon growth and guidance in multiple neural regions

  Peng Han, et al., bioRxiv - Neuroscience 2021

  Quote: ... Alcam (1:200, R&D Systems), Lhx9 (1:50 ...
• Cbln1 regulates axon growth and guidance in multiple neural regions

  Peng Han, et al., bioRxiv - Neuroscience 2021

  Quote: ... Robo3 (1:500, R&D Systems), Tag1 (1:200 ...
• Short-term exposure to intermittent hypoxia leads to changes in gene expression seen in chronic pulmonary disease

  Gang Wu, et al., bioRxiv - Pathology 2020

  Quote: ... FOXFI (1:100, R&D Systems), HOPX (1:100 ...
• Short-term exposure to intermittent hypoxia leads to changes in gene expression seen in chronic pulmonary disease

  Gang Wu, et al., bioRxiv - Pathology 2020

  Quote: ... EMCN (1:200, R&D Systems), FOXFI (1:100 ...
• Mechanical Instability of Adherens Junctions Overrides Intrinsic Quiescence of Hair Follicle Stem Cells

  Ritusree Biswas, et al., bioRxiv - Cell Biology 2020

  Quote: ... Lrig1(1:500, R&D System), Lef1 (1:200) ...
• Anthrax Toxin as a Molecular Platform to Target Nociceptive Neurons and Modulate Pain

  Nicole J. Yang, et al., bioRxiv - Neuroscience 2020

  Quote: ... (R&D Systems, #AF1056, 1:500), goat polyclonal anti-TRPV1 (R&D Systems ...
• HES1 is a Critical Mediator of the SHH-GLI3 Axis in Regulating Digit Number

  Deepika Sharma, et al., bioRxiv - Developmental Biology 2020

  Quote: ... GLI3 (1:1000; R&D systems); P27 (1:1000 ...
• Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells

  Nicole Aaron, et al., bioRxiv - Molecular Biology 2021

  Quote: ... SB290157 (R&D Systems, 1 μM), were added to the medium 2 days before induction and included in the maintenance media when necessary ...
• Astroglial exosome HepaCAM signaling and ApoE antagonization coordinates early postnatal cortical pyramidal neuronal axon growth and dendritic spine formation

  Shijie Jin, et al., bioRxiv - Neuroscience 2023

  Quote: ... Sparc (1:200, R&D Systems), Sema3a (1:200 ...
• Astroglial exosome HepaCAM signaling and ApoE antagonization coordinates early postnatal cortical pyramidal neuronal axon growth and dendritic spine formation

  Shijie Jin, et al., bioRxiv - Neuroscience 2023

  Quote: ... Hevin (1:200, R&D Systems), Sparc (1:200 ...
• Hypoxia regulate developmental coronary angiogenesis potentially through VEGFR2- and SOX17-mediated signaling

  Halie E. Vitali, et al., bioRxiv - Developmental Biology 2023

  Quote: ... SOX17 (1:100, R&D systems). Samples were rocked overnight at 4°C ...
• Endothelial SMAD1/5 signaling couples angiogenesis to osteogenesis during long bone growth

  Annemarie Lang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... CD31/PECAM-1 (R&D Systems; catalog number ...
• PROX1 inhibits PDGF-B expression to prevent myxomatous degeneration of heart valves

  Yen-Chun Ho, et al., bioRxiv - Developmental Biology 2023

  Quote: ... (R&D systems; AF743; 1:400) and GFP (Abcam ...
• Time series scRNAseq analysis in mouse and human informs optimization of rapid astrocyte differentiation protocols

  PW Frazel, et al., bioRxiv - Neuroscience 2023

  Quote: ... 1:100 (R&D system, #AF2864); chicken MAP2 ...
• Forward genetic screens identify mechanisms of resistance to small molecule lactate dehydrogenase inhibitors

  Anderson R Frank, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 1:10,000 (R&D Systems MAB9205); anti-GFP ...
• Directed differentiation of functional corticospinal-like neurons from endogenous SOX6+/NG2+ cortical progenitors

  Abdulkadir Ozkan, et al., bioRxiv - Neuroscience 2024

  Quote: ... 1:100 (R&D Systems; MAB3314); goat anti-OLIG2 ...
• Directed differentiation of functional corticospinal-like neurons from endogenous SOX6+/NG2+ cortical progenitors

  Abdulkadir Ozkan, et al., bioRxiv - Neuroscience 2024

  Quote: ... 1:200 (R&D Systems, AF2418); rat anti-RFP ...
• Cellular signalling protrusions enable dynamic distant contacts in spinal cord neurogenesis

  Joshua Hawley, et al., bioRxiv - Developmental Biology 2024

  Quote: ... 1:100 (R&D Systems AF5026). Secondary antibody ...
• Angiogenic and Immune Predictors of Neoadjuvant Axitinib Response in Renal Cell Carcinoma with Venous Tumour Thrombus

  Rebecca Wray, et al., bioRxiv - Cancer Biology 2024

  Quote: ... PD-1 (AF1086, R&D Systems), CD4 (EPR6855 ...
• Axin1 and Axin2 regulate the WNT-signaling landscape to promote distinct mesoderm programs

  Rocío Hernández-Martínez, et al., bioRxiv - Developmental Biology 2024

  Quote: ... GFP (1:500, R&D Systems), SOX2 (1:400 Cell Signaling) ...
• Axin1 and Axin2 regulate the WNT-signaling landscape to promote distinct mesoderm programs

  Rocío Hernández-Martínez, et al., bioRxiv - Developmental Biology 2024

  Quote: ... FOXF1 (1:300, R&D Systems), TBX6 (1:300 ...
• Axin1 and Axin2 regulate the WNT-signaling landscape to promote distinct mesoderm programs

  Rocío Hernández-Martínez, et al., bioRxiv - Developmental Biology 2024

  Quote: ... TBX6 (1:300, R&D Systems), pSMAD1/5/9 (1:100 Cell Signaling) ...
• Deep skin fibroblast-mediated macrophage recruitment supports acute wound healing

  Veronica M. Amuso, et al., bioRxiv - Cell Biology 2024

  Quote: ... ITGA6 (R&D Systems, 1:300), and pH3 (Abcam ...
• Aberrant activation of Wnt/β-Catenin signaling pathway drives the expression of poor prognosis-associated microRNAs in adrenocortical cancer with a major impact on miR-139-5p and its host gene PDE2A

  Justine Cristante, et al., bioRxiv - Cancer Biology 2023

  Quote: The blots were probed overnight at 4°C with monoclonal mouse anti-β-Catenin (2 µg/mL in Bovine Serum Albumin 3%, R&D Systems, Minneapolis, USA, #MAB1329), monoclonal rabbit anti-NDRG4 (1:1000 ...
• Tracking Adoptive T Cell Therapy Using Magnetic Particle Imaging

  Angelie Rivera-Rodriguez, et al., bioRxiv - Bioengineering 2020

  Quote: ... Tumor cells were resuspended in 1x PBS and mixed with methylcellulose (1:1 ratio) (R&D Systems). 8- to 10-week old naïve C57BL/6 mice were anesthetized with isoflurane and placed in a stereotactic frame ...
• Epigenetic downregulation of HER2 during EMT leads to tumor resistance to HER2-targeted therapies in breast cancer

  Babak Nami, Avrin Ghanaeian, Zhixiang Wang, bioRxiv - Cancer Biology 2020

  Quote: ... anti-human sFRP-1 and antihuman Dkk-1 antibodies (cat# CCM017; R&D Systems; Minneapolis, MN, USA) for 15 days ...
• On-chip engineered human lymphatic microvasculature for physio-/pathological transport phenomena studies

  Jean C. Serrano, et al., bioRxiv - Bioengineering 2022

  Quote: ... Alexa Fluor® 647-conjugated anti-human lymphatic vessel endothelial receptor-1 (LYVE-1 ,R&D Systems) or Alexa Fluor™ 488-conjugated anti-human laminin (R&D Systems ...
• Neural precursor cells contribute to decision-making by tuning striatal connectivity via secretion of IGFBPL-1

  Erica Butti, et al., bioRxiv - Neuroscience 2020

  Quote: ... Primary antibodies used: purified goat anti mouse IGFBPL-1 (R&D Systems, product no: AF4130, (1:50)) ...
• Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming

  Corey D. Holman, et al., bioRxiv - Developmental Biology 2024

  Quote: ... and anti-mouse CD142 (Sino Biological, 50413-R001, 1:100; or R&D Systems, AF3178, 1:50). Anti-mouse CD142 antibodies were conjugated with Biotium Mix-n-Stain CF647 (Sigma ...
• Rampant transcription replication conflict creates therapeutic vulnerability in extrachromosomal DNA containing cancers

  Jun Tang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... were coated with 50 µL of 1:1 Poly- L-Lysine (R&D Systems, #3438-100-01) and Poly-D-Lysine (R&D Systems ...
• Vascular Endothelial-derived SPARCL1 Exacerbates Viral Pneumonia Through Pro-Inflammatory Macrophage Activation

  Gan Zhao, et al., bioRxiv - Immunology 2023

  Quote: ... slides were probed with primary antibodies (CD31 1:200, Biolegend, MEC13.3; mSPARCL1 1:500, R&D systems, #AF2836-SP ...
• A Soluble Platelet-Derived Growth Factor Receptor-β Originates via Pre-mRNA Splicing in the Healthy Brain and is Differentially Regulated during Hypoxia and Aging

  Laura Beth Payne, et al., bioRxiv - Cell Biology 2023

  Quote: ... goat anti-CD31/platelet-endothelial cell adhesion molecule-1 (PECAM-1) antibody (R&D Systems, AF3628,1:500), and rabbit anti-glial-fibrillary acidic protein (GFAP ...
• BMP4 regulates asymmetric Pkd2 distribution in mouse nodal immotile cilia and ciliary mechanosensing required for left–right determination

  Takanobu A. Katoh, et al., bioRxiv - Developmental Biology 2024

  Quote: ... 1 μg/mL Noggin and 1 μg/mL Chordin as double treatment (758-CN; R&D Systems), 2% v/v of PBS containing 0.1% BSA as the control Noggin and Chordin double treatment ...
• Cloning and functional characterization of novel human neutralizing anti-interferon-alpha and anti-interferon-beta antibodies

  Emmanouil Papasavvas, et al., bioRxiv - Immunology 2024

  Quote: ... human recombinant IFN-α2a (1 µg/ml) and IFN-β (1 µg/ml) proteins (R&D Systems) were reduced using NuPAGE Sample Reducing Agent (10x ...
• An mRNA SARS-CoV-2 vaccine employing Charge-Altering Releasable Transporters with a TLR-9 agonist induces neutralizing antibodies and T cell memory

  Ole A.W. Haabeth, et al., bioRxiv - Immunology 2021

  Quote: ... After washing wells were incubated with a 5-bromo-4-chloro-3⍰-indolyl phosphate (BCIP)/nitro blue tetrazolium (NBT) substrate (R&D systems, mouse IFNγ Kit Cat # EL485). Plates were scanned and analyzed using ImmunoSpot Microanalyzer.
• Alveoli form directly by budding led by a single epithelial cell

  Astrid Gillich, et al., bioRxiv - Developmental Biology 2021

  Quote: ... in serum-free media (DMEM/F12 supplemented with L-glutamine and penicillin-streptomycin) with added FGF ligands (Fgf7; 4 µM, R&D Systems, Cat. No. 5028-KG-025), the γ-secretase inhibitor DAPT (10 µM ...
• IgG derived dendritic cells can induce production of IL-17 by T cells in multiple sclerosis

  Nazanin Pournasrolla, et al., bioRxiv - Immunology 2022

  Quote: ... immobilized hIgG, or 50 ng/ml recombinant GM-CSF (rGM-CSF) (Bioscience, US) plus 20 ng/ml IL-4 (R&D systems Cat.No. 204-IL-010, US), for 5 days to obtain immature dendritic cells (iDC) ...
• Benchmarking organ-specific responses to therapies in tissues differentiated from Cystic Fibrosis patient derived iPSCs

  Abdelkader Daoud, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... the DE monolayer was incubated for 4 days with the hindgut induction medium supplemented with 500 ng/mL of FGF4 (R&D Systems, cat # 235-F4-025/CF) and 3μM of CHIR99021 (STEMCELL Technologies ...
• Notch signaling determines cell-fate specification of the two main types of vomeronasal neurons of rodents

  Raghu Ram Katreddi, et al., bioRxiv - Developmental Biology 2021

  Quote: ... Goat anti-Dll4 (*with antigen retrieval 1:50 and without antigen retrieval 1:25, AF1389, R&D Systems), *Rabbit anti-NICD activated (1:75 ...
• SARS-CoV-2 promotes microglial synapse elimination in human brain organoids

  Samudyata, et al., bioRxiv - Neuroscience 2022

  Quote: ... 1% P/S and 0.l l⍰lμ gl⍰lml-1 of interleukin (IL)-34 (R&D Systems) and 0.01 μg ml −1 of granulocyte macrophage colony-stimulating factor (GM-CSF ...
• The RNA helicases DDX5 and DDX17 facilitate neural differentiation of human pluripotent stem cells NTERA2

  Praewa Suthapot, et al., bioRxiv - Neuroscience 2021

  Quote: ... the samples were stained with TRA-1-60 conjugated FITC antibody (R&D system, FAB4770G, 1:50 dilution) or normal IgM conjugated FITC (Sigma ...