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1 - 15 of 15 citations for Tubulin inhibitor 1 since 2019

• Predicting Individual Cell Division Events from Single-Cell ERK and Akt Dynamics

  Alan D Stern, et al., bioRxiv - Systems Biology 2021

  Quote: ... MK2206 (#CT-MK2206) (Akt inhibitor 1) was purchased from Chemietek.
• MCL1 dependence across MDS subtypes and dual inhibition of MCL1 and BCL2 in MISTRG6 mice

  Melissa A. Fischer, et al., bioRxiv - Cancer Biology 2020

  Quote: ... BCL2 inhibitor (venetoclax; Chemietek), or BCL-xL inhibitor (A-1155463 ...
• Integrated Phosphoproteomics and Transcriptional Classifiers Reveal Hidden RAS Signaling Dynamics in Multiple Myeloma

  Yu-Hsiu Tony Lin, et al., bioRxiv - Cancer Biology 2019

  Quote: ... MEK1 inhibitor trametinib (ChemieTek), mTOR inhibitor INK128 (LC Labs) ...
• Targeting the dependence on PIK3C3-mTORC1 signaling in dormancy-prone breast cancer cells blunts metastasis initiation

  Islam E. Elkholi, et al., bioRxiv - Cancer Biology 2023

  Quote: The PIK3CA-inhibitor BYL719 (ChemieTek), AKT-inhibitor MK-2206 2HCl (Selleck Chemicals #S1078) ...
• NEDD8 activity is important for direct antigen MHC class I antigen presentation

  Kartikeya Vijayasimha, et al., bioRxiv - Immunology 2022

  Quote: ... The ubiquitin E1 inhibitor MLN7243 (ChemieTek), and NEDD8 E1 inhibitor MLN4924 (Millipore ...
• “Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression”

  Marie C. Hasselluhn, et al., bioRxiv - Cancer Biology 2023

  Quote: ... LDE225 (SMO inhibitor; ChemieTek, CT-LDE225), IgG (InVivoMab rat IgG1 isotype control ...
• MCL1 dependence across MDS subtypes and dual inhibition of MCL1 and BCL2 in MISTRG6 mice

  Melissa A. Fischer, et al., bioRxiv - Cancer Biology 2020

  Quote: ... or BCL-xL inhibitor (A-1155463; Chemietek) at concentrations from 3nM to 10µM ...
• The MSP-RON axis stimulates cancer cell growth in models of triple negative breast cancer

  Rhona Millar, et al., bioRxiv - Cancer Biology 2020

  Quote: ... The RON inhibitor BMS-777607 (ChemieTek #CT-BMS777) was added to cells at 1μM for 1h before MSP treatment where indicated.
• Histone deacetylase inhibitor induces acetyl-CoA depletion leading to lethal metabolic stress in RAS-pathway activated cells

  Agnes Basseville, et al., bioRxiv - Cancer Biology 2022

  Quote: ... MK-2206 (AKT inhibitor) were purchased from ChemieTek (Indianapolis, IN). Glutaminase inhibitor 968 compound was obtained from Millipore (Burlington ...
• TNFR2 induced priming of NLRP3-inflammasome via RIPK1 leads to pyroptosis in XIAP deficient cells

  Janin Knop, et al., bioRxiv - Immunology 2019

  Quote: ... Inhibitors were used at the following concentrations: Birinapant (500nM, Chemietek), Compound A (500nM ...
• Comprehensive isotopomer analysis of glutamate and aspartate in small tissue samples

  Feng Cai, et al., bioRxiv - Biochemistry 2022

  Quote: ... For studies that involved treatment with the complex I inhibitor (IACS-010759, ChemieTek), the mice were administered IACS-010759 by oral gavage every day for 5 days (10 mg/kg body mass in 100 μL of 0.5% methylcellulose and 4% DMSO ...
• Hypoxia induces transcription of DOT1L in articular cartilage to protect against osteoarthritis

  Astrid De Roover, et al., bioRxiv - Cell Biology 2021

  Quote: ... Micromasses were treated with vehicle (DMSO) or DOT1L inhibitor EPZ-5676 (EPZ) (10µM) (Chemietek) under normoxic (21% O2 ...
• MCL1 dependence across MDS subtypes and dual inhibition of MCL1 and BCL2 in MISTRG6 mice

  Melissa A. Fischer, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and 1x L-GlutaMAX) and treated for 48 hours with an MCL1 inhibitor (S63845; Chemietek, Indianapolis, IN), BCL2 inhibitor (venetoclax ...
• Proteome-scale induced proximity screens reveal highly potent protein degraders and stabilizers

  Juline Poirson, et al., bioRxiv - Molecular Biology 2022

  Quote: Cells were treated with 1 µM MLN4924 (Chemietek) for 24 hours ...
• A versatile, chemically-controlled DNA binding switch enables temporal modulation of Cas9-based effectors

  Cindy T. Wei, et al., bioRxiv - Molecular Biology 2022

  Quote: ... a final concentration of 1 μM of A-1155463 (A115; ChemieTek) was added to the cells ...