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1 - 9 of 9 citations for Npc 15437 dihydrochloride since 2020

• Properties of Alzheimer’s disease brain-derived tau aggregates define tau processing by human astrocytes

  Matthew J. Reid, et al., bioRxiv - Neuroscience 2024

  Quote: NPCs were differentiated into astrocytes using Astrocyte Medium (ScienCell, Cat# 1801). NPCs were plated at a low density (15,000 cells/cm² ...
• IL-1Ra and CCL5, but not IL-10, are promising targets for treating SMA astrocyte-driven pathology

  Reilly L. Allison, et al., bioRxiv - Neuroscience 2023

  Quote: ... P3 NPCs were used for astrocyte differentiations and cultured in ScienCell Astrocyte Medium (ScienCell Research Laboratories ...
• Development of MAPT S305 mutation models exhibiting elevated 4R tau expression, resulting in altered neuronal and astrocytic function

  KR Bowles, et al., bioRxiv - Neuroscience 2023

  Quote: ... NPCs were seeded sparsely into Matrigel-coated plates and treated with Astrocyte media (ScienCell) as previously described84 ...
• The mitochondrial unfolded protein response promotes senescence in human microglia by increasing S-adenosylmethionine availability for polyamine synthesis

  Maria Jose Perez J., et al., bioRxiv - Neuroscience 2024

  Quote: ... NPCs were seeded at a density of 15,000 cells/cm² in a commercial astrocyte differentiation medium (ScienCell Research Laboratories ...
• APOE2, E3 and E4 differentially modulate cellular homeostasis, cholesterol metabolism and inflammatory response in isogenic iPSC-derived astrocytes

  Sherida M. de Leeuw, et al., bioRxiv - Neuroscience 2021

  Quote: ... NPCs were differentiated to astrocytes by the application of Primary Astrocyte Medium (AM; ScienCell: 1801, astrocyte medium (1801-b), 2% FCS (0010) ...
• ALS iPSC-derived microglia and motor neurons respond to astrocyte-targeted IL-10 and CCL2 modulation

  Reilly L. Allison, Allison D. Ebert, bioRxiv - Neuroscience 2023

  Quote: ... NPCs were passaged every 6 days and on passage 3 were differentiated into astrocytes using ScienCell Astrocyte Medium (ScienCell Research Laboratories ...
• The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases uncovers cholesterol as a regulator of astrocyte reactivity impaired by ApoE4

  Femke M. Feringa, et al., bioRxiv - Neuroscience 2024

  Quote: ... One week after cell scraping of the NPCs the NMM medium was exchanged for astrocyte medium (AM; ScienCell, 1801) and afterwards medium was refreshed 3 times a week for the following 2 weeks ...
• The LRRK2 G2019S mutation alters astrocyte-to-neuron communication via extracellular vesicles and induces neuron atrophy in a human iPSC-derived model of Parkinson’s disease

  Aurelie de Rus Jacquet, et al., bioRxiv - Neuroscience 2021

  Quote: ... NPCs were plated on Geltrex-coated plates at 15,000 cells/cm2 in ScienCell astrocyte medium (ScienCell Research Laboratories, Carlsbad, CA), passaged every 7 days at 15,000 cells/cm2 ...
• mTOR controls neurotoxic lysosome exocytosis in inflammatory reactive astrocytes

  Brendan Rooney, et al., bioRxiv - Cell Biology 2021

  Quote: ... these NPCs were re-plated on 1:200 Matrigel-coated dishes and cultured with ScienCell Astrocyte Media (ScienCell Research Laboratories cat. no. 1801) + 2 μg/mL doxycycline (Millipore Sigma cat ...