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551 - 600 of 3238 citations for 3 2 5 Dioxoimidazolidin 4 yl propanoic acid since 2020

• p53 restoration in small cell lung cancer identifies a latent Cyclophilin-dependent necrosis mechanism

  Jonuelle Acosta, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Cleaved Caspase-3 (1:1000,Cell Signaling Technology, 9661S), Cleaved PARP (1:1000,Cell Signaling Technology ...
• Repurposing of the multiciliation gene regulatory network in fate specification of Cajal-Retzius neurons

  Matthieu X Moreau, et al., bioRxiv - Developmental Biology 2022

  Quote: ... rabbit anti-Caspase 3 (Cell Signaling 9664, 1:400), mouse anti-FOP (Abnova H00011116-M01 1:500) ...
• Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis

  Zaili Luo, et al., bioRxiv - Cancer Biology 2022

  Quote: ... rabbit anti-Cleaved Caspase 3 (Cell Signaling, Cat#9661) and mouse-anti BrdU (BD Bioscience ...
• TRPV1-mediated sonogenetic neuromodulation of motor cortex in freely moving mice

  Kevin Xu, et al., bioRxiv - Bioengineering 2022

  Quote: ... or anti-Caspase-3 antibody (Cell Signaling, 1:2500), as well as DAPI mounting medium (Vector) ...
• Spatial regulation of the glycocalyx component Podocalyxin is a switch for pro-metastatic function

  Alvaro Román-Fernández, et al., bioRxiv - Cell Biology 2022

  Quote: FFPE sections for Galectin-3 (Gal3) (87985, Cell Signaling) IHC staining were dewaxed using an Agilent pre-treatment module ...
• Expression bias in retinoic acid responsive genes defines variations in neural differentiation of human pluripotent stem cells

  Suel-Kee Kim, et al., bioRxiv - Neuroscience 2022

  Quote: ... p-SMAD2/3 (8828, Cell Signaling Technology, 1:200), and TUJ1 (PRB-435P ...
• p53 promotes revival stem cells in the regenerating intestine after severe radiation injury

  Clara Morral, et al., bioRxiv - Cell Biology 2023

  Quote: ... cleaved caspase-3 (Asp175) (5A1E) (#9664; Cell Signaling Technology), or p53 (CM5 ...
• Cbl and Cbl-b Ubiquitin Ligases are Essential for Intestinal Epithelial Stem Cell Maintenance

  Neha Zutshi, et al., bioRxiv - Cell Biology 2023

  Quote: ... phospho-histone 3 (Ser10) (Cat# 9701, Cell Signaling Technology), and Villin-1 (Cat# 2369 ...
• The tricellular junctional protein Ildr2 helps maintain glomerular podocyte architecture

  Gary F. Gerlach, Yubin Xiong, Lori L. O’Brien, bioRxiv - Physiology 2024

  Quote: ... rabbit anti-Cleaved Caspase-3 (CC3) (Cell Signaling, 9661S) [1:500] ...
• Corticosteroids prevent pathological angiogenesis yet compromise reparative vascular remodeling in the retina

  Masayuki Hata, et al., bioRxiv - Immunology 2024

  Quote: ... and Cleaved Caspase-3 (Cat# 9661S, Cell Signaling Technologies) were diluted using the same solution and applied on the tissue overnight at 4°C ...
• Altered liver metabolism post-wean abolishes efficacy of vitamin D for breast cancer prevention in a mouse model

  Sarah M Bernhardt, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Cycle 3 Ki67 (Cell Signaling, 12202, 1:800, 1hr), Cycle 4 Tox1 (Abcam ...
• Macrophages allocate independent of apoptosis and produce reactive oxygen species during interdigital phagocytosis

  David Hernández-García, et al., bioRxiv - Developmental Biology 2024

  Quote: ... rabbit anti-active caspase 3 (aCasp3; 9664S, Cell Signaling); 1:500 ...
• Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 lineages combining increased fitness and antibody evasion

  Delphine Planas, et al., bioRxiv - Microbiology 2024

  Quote: ... rabbit anti-cleaved caspase-3 (D175; Cell Signaling Technology) and phalloidin-Atto 565/633 (75784-1MG-F ...
• Chromatin Remodelling in Damaged Intestinal Crypts Orchestrates Redundant TGFβ and Hippo Signalling to Drive Regeneration

  Mardi Fink, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Rabbit anti-Smad2/3 (Cell Signaling, #8685S, 1:300), Rabbit anti-pSmad2 (Cell signaling ...
• Astrocyte-derived PEA116 increases adult hippocampal neurogenesis and confers stress resilience

  Carron Charline, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit anti-Caspase-3 (1:500, Cell Signaling 9661S). Sections were then incubated for 1h15 at room temperature with the corresponding fluorescent secondary antibodies ...
• Natural Killer Cell Dysfunction In Human Bladder Cancer Is Caused By Tissue-Specific Suppression of SLAMF6 Signaling

  Adam M. Farkas, et al., bioRxiv - Immunology 2024

  Quote: ... Tim-3 (Clone D5D5RTM, Cell Signaling Technology, 2ug/mL) and PD-1 (Clone NAT-105 ...
• Depletion of TDP-43 exacerbates tauopathy-dependent brain atrophy by sensitizing vulnerable neurons to caspase 3-mediated endoproteolysis of tau in a mouse model of Multiple Etiology Dementia

  Meghraj S Baghel, et al., bioRxiv - Neuroscience 2024

  Quote: ... cleaved Caspase 3 (1:1000; D3E9; Cell Signaling Technology), Tuj1 (1:500 ...
• DNA Damage Response Deficiency Enhances Neuroblastoma Progression and Sensitivity to Combination PARP and ATR Inhibition

  Madeline N. Hayes, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and Cleaved-caspase 3 staining (Cell Signaling, Asp175, 5A1E). Tumors were dissected and lysed for protein detection by Western blot using antibodies against phospho-Rb Ser807/811 (Cell Signaling ...
• Removal of the catalytic subunit of DNA-protein kinase in the proximal tubules promotes DNA and tubular damage during kidney injury

  M. Swanson, et al., bioRxiv - Physiology 2024

  Quote: ... cleaved caspase-3 (cat #9661, 1:200; Cell Signaling), and Ki67 (cat #15580 ...
• Tumour-derived LAMA5 is critical for tumour initiation and controls progression and phenotype in luminal breast cancer

  Alexandra Ritchie, et al., bioRxiv - Cancer Biology 2024

  Quote: ... The primary antibody (Active caspase-3, Cell Signaling Technologies) was incubated in the IF buffer overnight at +4°C ...
• A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease

  Jiyi Pang, et al., bioRxiv - Cell Biology 2024

  Quote: ... the primary antibodies were: caspase-3 (Cell Signaling; 9662), caspase-8 (Cell Signaling ...
• The pro-apoptotic effect of chronic contractile activity-induced extracellular vesicles on Lewis Lung Carcinoma cells

  Patience O. Obi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-caspase-3 (9662, Cell Signaling, 1:1000), rabbit anti-cleaved caspase-3 (9661 ...
• A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease

  Jiyi Pang, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-cleaved-caspase-3 (Cell Signaling Technology, #9661) and iNOS (R&D MAB9502 ...
• Integration of sexual dimorphism and left-right asymmetry in the development of the duck syrinx

  Darcy Mishkind, et al., bioRxiv - Developmental Biology 2024

  Quote: Cleaved Caspase-3 (Cell Signaling Technology Asp175 Cat. #9661S) at 1:400 ...
• KSR1 knockout mouse model demonstrates MAPK pathway’s key role in cisplatin- and noise-induced hearing loss

  Matthew A. Ingersoll, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-p-ERK1/2 (Thr202/Tyr204, 9101S), anti-MEK1/2 (9122S), and anti-p-MEK1/2 (Ser217/221, 41G9S) were obtained from Cell Signaling Technologies, and anti-α Tubulin (T9026 ...
• Latrophilins are essential for endothelial junctional fluid shear stress mechanotransduction

  Keiichiro Tanaka, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Anti-Phospho-Smad1/5 (Cell signaling) (13820) ...
• Unbiased and UMI-informed sequencing of cell-free miRNAs at single-nucleotide resolution

  M.A.J. van Eijndhoven, et al., bioRxiv - Genomics 2021

  Quote: ... Exportin 5 (#12565S; Cell Signaling Technology), Dicer (#5362 ...
• Human GBP1 promotes pathogen vacuole rupture and inflammasome activation during Legionella pneumophila infection

  Antonia R. Bass, Sunny Shin, bioRxiv - Microbiology 2020

  Quote: ... caspase-5 (D3G4W; 46680S; Cell Signaling), Gasdermin-D (126-138 ...
• An isogenic human iPSC model unravels neurodevelopmental abnormalities in SMA

  Tobias Grass, et al., bioRxiv - Neuroscience 2023

  Quote: ... and 5% NGS (Cell Signaling, 5424S), immunostained with the indicated primary antibodies for 2h at RT and secondary antibodies for 1h at RT ...
• Optogenetic Instruction of Cell Fate by Temporal Patterning of Mechanobiological Signals

  Rocío G. Sampayo, et al., bioRxiv - Cancer Biology 2022

  Quote: ... pSMAD1/5 (1:400, Cell Signaling), mCherry (1:1000 ...
• Bone morphogenetic protein (BMP) signaling determines neuroblastoma cell fate and sensitivity to retinoic acid

  Min Pan, et al., bioRxiv - Cancer Biology 2024

  Quote: ... pSMAD1/5/9 (Cell Signaling, # 13820S), ACVR1 (Abcam ...
• PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification

  José Antonio Valer, et al., bioRxiv - Molecular Biology 2024

  Quote: ... p-SMAD1/5 (Cell Signaling, 9516), and vinculin (Sigma ...
• Rudhira-mediated microtubule stability controls TGFβ signaling during mouse vascular development

  Divyesh Joshi, et al., bioRxiv - Cell Biology 2024

  Quote: ... pSmad1/5/8 (Cell Signaling Technology), GAPDH (Sigma Chemical Co. ...
• Secreted exosomes induce filopodia formation

  Caitlin McAtee, et al., bioRxiv - Cell Biology 2024

  Quote: ... pSmad1/5/9 (Cell Signaling #13820) and Smad1 (Cell Signaling #6944 ...
• ECSIT prevents Alzheimer’s disease pathology by regulating neuronal mitochondrial ROS and mitophagy

  Alice Lepelley, et al., bioRxiv - Neuroscience 2020

  Quote: ... Lysate was incubated for 4 h at 4°C with anti-ECSIT2 antibody39 or IgG control (Cell Signaling, #2729), followed by overnight precipitation with 30 µL of washed Protein A sepharose 4B beads (Invitrogen) ...
• Impact of Type II LRRK2 inhibitors on signalling and mitophagy

  Anna Tasegian, et al., bioRxiv - Neuroscience 2021

  Quote: ... The anti (pan)14-3-3 rabbit polyclonal antibody (#8312) and anti α-tubulin mouse monoclonal antibody (clone DM1A, mAb #3873) were purchased from Cell Signaling Technology. Anti-glyceraldehyde-3-phosphate dehydrogenase (GAPDH ...
• Capitella teleta gets left out: Possible evolutionary shift causes loss of left tissues rather than increased neural tissue from dominant-negative BMPR1

  Nicole B. Webster, Néva P. Meyer, bioRxiv - Developmental Biology 2023

  Quote: ... and 1:400 rabbit anti-phosphorylated-SMAD1/5/8 (pSMAD1/5/8; clone 41D10, Cell Signaling Technologies). Secondary antibodies used were as follows ...
• Effects of Emodin, a Plant-Derived Anthraquinone, on TGF-β1-Induced Cardiac Fibroblast Activation and Function

  Wayne Carver, et al., bioRxiv - Cell Biology 2021

  Quote: ... ERK1/2 or pERK1/2 (all from Cell Signaling Technology Inc, Danvers, MA, www.cellsignal.com). Nitrocellulose membranes were rinsed and incubated in horseradish peroxidase- conjugated anti-rabbit or anti-mouse serum as appropriate ...
• “Metabolic dysregulations of cancer cells with metastatic potential”

  Sara Abdul Kader, et al., bioRxiv - Cancer Biology 2021

  Quote: ... MMP-2 (Cell signaling, #40994), Vimentin (Cell signaling ...
• Increased apoptotic priming of glioblastoma enables therapeutic targeting by BH3-mimetics

  Anna L Koessinger, et al., bioRxiv - Cancer Biology 2021

  Quote: ... pERK1/2 (Cell Signaling #4370), AKT (Cell Signaling #9272) ...
• Increased apoptotic priming of glioblastoma enables therapeutic targeting by BH3-mimetics

  Anna L Koessinger, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ERK1/2 (Cell Signaling #4695), pERK1/2 (Cell Signaling #4370) ...
• Increased apoptotic priming of glioblastoma enables therapeutic targeting by BH3-mimetics

  Anna L Koessinger, et al., bioRxiv - Cancer Biology 2021

  Quote: ... BCL-2 (Cell Signaling #2762), BCL-xL (Cell Signaling #2762) ...
• Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD⁺ signaling

  Mustafa N. Okur, et al., bioRxiv - Cell Biology 2020

  Quote: ... mitofusin 2 (Cell signaling, #9482), total OXHOS rodent cocktail (Abcam ...
• Peroxisome counteracts oxidative stresses by suppressing catalase import via Pex14 phosphorylation

  Kanji Okumoto, et al., bioRxiv - Cell Biology 2020

  Quote: ... and Erk1/2 (Cell Signaling), mouse monoclonal antibodies to HA (16B12 ...
• Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling

  Brian Czaya, et al., bioRxiv - Cell Biology 2021

  Quote: ... ERK1/2 (4695, Cell Signaling), STAT3 (4904 ...
• Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules

  Behnam Nabet, et al., bioRxiv - Cancer Biology 2020

  Quote: ... ERK1/2 (Cell Signaling, #4696), phospho-AKT S473 (Cell Signaling ...
• Peroxisome counteracts oxidative stresses by suppressing catalase import via Pex14 phosphorylation

  Kanji Okumoto, et al., bioRxiv - Cell Biology 2020

  Quote: ... phospho-Erk1/2 (Cell Signaling), cytochrome P450 reductase (Santa Cruz Biotechnology ...
• LAMC2 marks a tumor-initiating cell population with an aggressive signature in pancreatic cancer

  Donatella Delle Cave, et al., bioRxiv - Cancer Biology 2022

  Quote: ... MMP-2 (4022S, Cell Signaling), Vimentin (3932 ...
• COMBINATION THERAPIES TARGETING ALK-ABERRANT NEUROBLASTOMA IN PRECLINICAL MODELS

  Elizabeth R. Tucker, et al., bioRxiv - Cancer Biology 2022

  Quote: ... ERK1/2 (Cell Signaling #4695), pERK1/2 (Cell Signaling #9101) ...
• Hemodynamic stress activates inflammatory responses and cell death through spectrin-dependent modulation of Store Operated Calcium Entry

  Lance Hsieh, et al., bioRxiv - Cell Biology 2022

  Quote: ... ERK1/2 (4695, Cell Signaling), SPTAN1 (MAB1622 ...