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451 - 500 of 10000+ citations for 2 Bromo 1 5 bromofuran 2 yl ethanone since 2020

• Discovery of novel ID2 antagonists from pharmacophore-based virtual screening as potential therapeutics for glioma

  Genshen Zhong, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-MMP-2 (Cell Signaling Technology, #87809), anti-VEGFA (Cell Signaling Technology ...
• SHIP2 controls matrix mineralization by regulation of the RhoA/ROCK pathway and remodeling of the actin cytoskeleton

  Anais Fradet, Jamie Fitzgerald, bioRxiv - Cell Biology 2022

  Quote: ... Erk1/2 antibody (Cell Signaling Technologies #9107) 1/2000 ...
• Renal-Derived Human sPRR Does Not Increase Blood Pressure in High Fat Diet Mice

  Gertrude Arthur, et al., bioRxiv - Physiology 2024

  Quote: ... Aquaporin 2 (Cell Signaling Technology Inc, 3487) and GAPDH (Sigma Aldrich ...
• A high-throughput zebrafish screen identifies novel candidate treatments for Kaposiform Lymphangiomatosis (KLA)

  Ivan Bassi, et al., bioRxiv - Developmental Biology 2024

  Quote: ... phosphor-ERK1/2 (#4376, Cell Signaling, USA), and Podoplanin (M3619 ...
• Chitinase 3-like-1 (CHI3L1) Inhibits Innate Anti-Tumor and Tissue Remodeling Immune Responses by Regulating CD47-SIRPα and CD24-Siglec10-Mediated Phagocytosis

  Bing Ma, et al., bioRxiv - Immunology 2024

  Quote: ... and SHP-2 (Cell Signaling Technology, #3752) overnight at 4°C in TBST and 5% BSA ...
• MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer

  Olaf Klingbeil, et al., bioRxiv - Cancer Biology 2024

  Quote: ... p-LATS1/2 (T1079/T1041) (Cell Signaling, D57D3 ...
• Glioma-associated fibroblasts promote glioblastoma resistance to temozolomide through CCL2-CCR2 paracrine signaling

  Mingrong Zuo, et al., bioRxiv - Cancer Biology 2024

  Quote: ... total-ERK1/2 (Cell Signaling Technology #4696), Phospho-p38 MAPK (T180/Y182 ...
• Identifying and targeting key driver genes for collagen production within the 11q13/14 breast cancer amplicon

  Daniela Araiza-Olivera, et al., bioRxiv - Cancer Biology 2024

  Quote: ... -total ERK1/2 (Cell Signaling Tech #9102), -GAPDH (#4138).
• Cellular protection from H₂O₂ toxicity by Fv-Hsp70. Protection via catalase and gamma-glutamyl cysteine synthase

  Chris Hino, et al., bioRxiv - Cell Biology 2023

  Quote: ... and polyclonal Nrf 2 (Cell Signaling 336495). All antibodies were used at 1:1000 dilution in blocking buffer ...
• Oncogenic metabolic rewiring independent of proliferative control in human mammary epithelial cells

  Wentao Dong, et al., bioRxiv - Biochemistry 2022

  Quote: ... ERK1/2 (Cell Signaling, Cat. No. 9102) phospho-ERK1/2 (Cell Signaling ...
• PML mutants resistant to arsenic induced degradation fail to generate the appropriate SUMO and ubiquitin signals required for RNF4 and p97 recruitment

  Ellis G. Jaffray, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-SUMO- 2 (Cell signaling 4971S), rabbit FK2 ubiquitin (Enzo BML-PW8810-0500) ...
• Nischarin negatively impacts ShcD-mediated tumor cell migration

  Rayan A. Hago, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-Erk1/2 (cst4695-Cell Signaling, USA), anti-Nischarin (ab204588-Abcam ...
• Epigenomic Analyses Identify FOXM1 As a Key Regulator of Anti-Tumor Immune Response in Esophageal Adenocarcinoma

  Benjamin Ziman, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 2 μg FOXM1 antibody (Cell Signaling, 20459) was then added and incubated at 4 °C overnight on a rotating platform ...
• Spatiotemporal Proteomics Deciphers Functional Selectivity of EGFR ligands

  Akihiro Eguchi, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-Erk1/2 (#4695; Cell Signaling Technology) mouse anti-phospho-Erk1/2 (T202/T204 ...
• Multi-layered proteomics identifies insulin-induced upregulation of the EphA2 receptor via the ERK pathway and dependent on low IGF1R level

  Sarah Hyllekvist Jørgensen, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-ERK1/2 (Cell Signaling Technology); rabbit anti-Eph receptor A2 antibody (ab273118 and ab185156) ...
• Myocardin-related transcription factors regulate morphogenetic events in vertebrate embryos by controlling F-actin organization and apical constriction

  Keiji Itoh, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-Erk1/2 (9102, Cell Signaling), rabbit anti-phospho-Smad2 (3108S ...
• CRISPR screens reveal convergent targeting strategies against evolutionarily distinct chemoresistance in cancer

  Chunge Zhong, et al., bioRxiv - Cancer Biology 2024

  Quote: ... ERK1/2 (Cell Signaling Technology, Cat# 137F5), p21 (Proteintech ...
• Lipid droplet targeting of ABHD5 and PNPLA3 I148M is required to promote liver steatosis

  Grace Teskey, et al., bioRxiv - Cell Biology 2024

  Quote: ... Mek1/2 (Cell Signaling cat. No. S8727), AIF (Cell Signaling cat ...
• Testicular sex cord–stromal tumors in mice with constitutive activation of PI3K and loss of Pten

  Marija Dinevska, et al., bioRxiv - Cancer Biology 2024

  Quote: ... phospho-Erk1/2 (Cell Signaling Technologies 4370), phospho-Akt (Cell Signaling Technologies 4060 ...
• Sustained experimental activation of FGF8/ERK in the developing chicken spinal cord reproducibly models early events in ERK-mediated tumorigenesis

  Axelle Wilmerding, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-phospho-p44/42 MAPK (ERK1/2) (Thr202/Tyr204) 1:250 (Cell signaling #9101), rabbit anti-SOX2 1:500 (AB5603 Merck Millipore) ...
• MicroRNA-dependent inhibition of PFN2 orchestrates ERK activation and pluripotent state transitions by regulating endocytosis

  Carolyn Sangokoya, Robert Blelloch, bioRxiv - Developmental Biology 2020

  Quote: ... Phospho-p44/42 Erk1/2 Thr202/Tyr204 at 1:1000 dilution (Cell Signaling Technology, 4370), and p44/42 Erk1/2 at 1:1000 dilution (Cell Signaling Technology ...
• Reversal of β-amyloid induced microglial toxicity in vitro by activation of Fpr2/3

  Edward S. Wickstead, et al., bioRxiv - Neuroscience 2020

  Quote: ... or superoxide dismutase 2 (SOD2; rabbit monoclonal, 1:1000, Cell Signaling Technology, Leiden, The Netherlands) in Tris-buffer saline solution containing 0.1% Tween-20 and 5% (w/v ...
• Negative durotaxis: cell movement toward softer environments

  Aleksi Isomursu, et al., bioRxiv - Biophysics 2020

  Quote: ... rbt anti-p-ERK1/2 (T202/Y204) (Cell Signaling Technology, 4370, 1:1000 for WB), ms anti-YAP (Santa Cruz Biotechnology ...
• Kir6.2-containing K_ATP channels are necessary for glucose dependent increases in amyloid-beta and Alzheimer’s-related pathology

  John Grizzanti, et al., bioRxiv - Neuroscience 2022

  Quote: ... 2° antibody conjugated with HRP specific to either (1:3,000) goat anti-rabbit (Cell Signaling) or (1:3,000 ...
• Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer progression

  Jason J. Northey, et al., bioRxiv - Cancer Biology 2022

  Quote: ... phospho-p44/42 MAPK (ERK1/2) (T202/Y204) (Cell Signaling Technology, Cat. #: 9101, 1:200), NFκB p65 (D14E12 ...
• Purinergic receptor P2RY14 cAMP signaling regulates EGFR-driven Schwann cell precursor self-renewal and nerve tumor initiation in neurofibromatosis

  Jennifer Patritti-Cram, et al., bioRxiv - Neuroscience 2021

  Quote: ... P44/42 MAPK (Erk1/2) (137F5) rabbit mAB (1:1000, Cell Signaling Technologies, Cat#: 4695S).
• Biphasic Response of Protein Kinase A to Cyclic Adenosine Monophosphate Triggers Distinct Epithelial Phenotypes

  João Pedro Fonseca, et al., bioRxiv - Systems Biology 2020

  Quote: ... F(ab’)2 Fragment (Alexa Fluor® 488 Conjugate) (Cell Signaling Technology #4412, 1:1000).
• Biphasic Response of Protein Kinase A to Cyclic Adenosine Monophosphate Triggers Distinct Epithelial Phenotypes

  João Pedro Fonseca, et al., bioRxiv - Systems Biology 2020

  Quote: ... anti-p44/42 MAPK (Erk1/2) (L34F12) Mouse mAb (Cell signaling technology ##4696, 1:2000), anti-Phospho-p38 MAPK (Thr180/Tyr182 ...
• Long-term non-invasive drug treatments for adult zebrafish

  Yuting Lu, E. Elizabeth Patton, bioRxiv - Cancer Biology 2021

  Quote: ... total p44/42 MAPK (ERK1/2) primary antibody (1:200, rabbit, Cell Signaling Technologies #9102), and Alexa-fluor 488 secondary antibody (1:1000 ...
• KRAS G12D can be targeted by potent salt-bridge forming inhibitors

  Zhongwei Mao, et al., bioRxiv - Cancer Biology 2021

  Quote: ... slides were incubated with primary antibodies against pERK1/2 (1:200, Cell Signaling Technology, 4370), cleaved Caspase-3 (1:200 ...
• Differentiation signals from glia are fine-tuned to set neuronal numbers during development

  Anadika R. Prasad, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (1:100, Cell Signaling #9101), chicken anti-RFP (1:500 ...
• HD-PTP/PTPN23 hypomorphic mice display lipodystrophy

  Brian A. Davies, et al., bioRxiv - Cell Biology 2022

  Quote: ... total-p42/44 MAPK (ERK1/2) 3A7 mouse monoclonal antibody (1:2000, 9107, Cell Signaling), p-AKT-S473 D9E rabbit monoclonal antibody (1:1000 ...
• Murine gammaherpesvirus 68 ORF45 stimulates B2 retrotransposon and pre-tRNA activation in a manner dependent on mitogen-activated protein kinase (MAPK) signaling

  Azra Lari, Britt A. Glaunsinger, bioRxiv - Microbiology 2022

  Quote: ... anti-phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) antibody (Cell Signaling #9101, 1:1000), anti-Brf1polyclonal antibody (Bethyl ...
• Endosomal LRBA regulates the endo-lysosomal pathway

  Viktória Szentgyörgyi, et al., bioRxiv - Immunology 2024

  Quote: ... mouse monoclonal anti p44/42 MAPK (Erk1/2) (L334F10) antibody (#4696, Cell Signaling, 1:2000), rabbit polyclonal anti phospho-p44/42 MAPK (Erk1/2 ...
• Endosomal LRBA regulates the endo-lysosomal pathway

  Viktória Szentgyörgyi, et al., bioRxiv - Immunology 2024

  Quote: ... mouse monoclonal anti p44/42 MAPK (Erk1/2) (L334F10) antibody (#4696, Cell Signaling, 1:2000), rabbit polyclonal anti phospho-p44/42 MAPK (Erk1/2 ...
• Ca²⁺-driven cytoplasmic backflow secures spindle position in fertilized mouse eggs

  Takaya Totsuka, Miho Ohsugi, bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-phospho-myosin light chain 2 (Ser19) (pMLC) (1:100, Cell Signaling Technology #3671), for 2 hours ...
• Thrombospondin 2 is a key determinant of fibrogenesis in NAFLD

  Takefumi Kimura, et al., bioRxiv - Molecular Biology 2023

  Quote: ... small mothers against decapentaplegic (SMAD) 2/3 (D7/G7) (Cell Signaling Technology, #8685, 1:1,000), Phospho-Smad2 (Ser465/467)/Smad3 (Ser423/425 ...
• Combined KRAS^G12C and SOS1 inhibition enhances and extends the anti-tumor response in KRAS^G12C-driven cancers by addressing intrinsic and acquired resistance

  Venu Thatikonda, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Anti-phospho-p44/42 MAPK (ERK1/2) (Thr202/Tyr204) (1:2000, Cell Signaling Technology #4370) was developed using Opal tyramide signal amplification (TSA ...
• Oncogenic Kras^G12D specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination with immunotherapy regresses advanced PDAC in a CD8⁺ T cells dependent manner

  Krishnan K. Mahadevan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Anti-phospho-p44/42 MAPK (ERK1/2) (Thr202/Tyr204) (1:2000, Cell Signaling Technology #4370) was developed using Opal tyramide signal amplification (TSA ...
• Control of gastruloid patterning and morphogenesis by the Erk and Akt signaling pathways

  Evan J. Underhill, Jared E. Toettcher, bioRxiv - Developmental Biology 2023

  Quote: ... Erk1/2 phosphorylated at Thr202 and Tyr204 rabbit (Cell Signaling Technology, 4370, 1:200 dilution), phospho-Akt at Ser473 rabbit (Cell Signaling Technology ...
• Alterations in the preneoplastic breast microenvironment of BRCA1/2 mutation carriers revealed by spatial transcriptomics

  Anthony Caputo, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and 1:200 phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Cell Signaling Technology, 9101S). Primary antibodies used for immunohistochemistry of FFPE tissues were 1:50 COL6 (Rockland ...
• Influence of myosin regulatory light chain and myosin light chain kinase on hair cells of the inner ear

  Ryohei Oya, et al., bioRxiv - Biophysics 2023

  Quote: ... anti-phospho-myosin light chain 2 (3671; Cell Signaling Technology, Danvers, MA, USA; 1:50); Alexa Fluor 488-labeled secondary antibody (Thermo Fisher Scientific ...
• Fate plasticity of interneuron specification

  Mohammed A. Mostajo-Radji, et al., bioRxiv - Neuroscience 2024

  Quote: Rabbit anti-MAPK (ERK1/2) phosphorylated (T202/Y204) (Cell Signaling # 9101; RRID: AB_331646; 1:100)
• Cyclin A/B RxL Macrocyclic Inhibitors to Treat Cancers with High E2F Activity

  Shilpa Singh, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Cells were then incubated with 1 μg/ml DAPI (4,6-diamidino-2-phenylindole, Cell Signaling) for 5 min ...
• Cell surface ribonucleoproteins cluster with heparan sulfate to regulate growth factor signaling

  Peiyuan Chai, et al., bioRxiv - Molecular Biology 2024

  Quote: ... mouse monoclonal anti-p44/42 MAPK (Erk1/2) (Cell Signaling Technology, 4370S, immunoblot 1:500). Secondary antibodies used ...
• Astrocyte-derived PEA116 increases adult hippocampal neurogenesis and confers stress resilience

  Carron Charline, et al., bioRxiv - Neuroscience 2024

  Quote: ... Plates were incubated with primary antibodies rabbit anti-ERK1/2 (1/500, Cell Signaling 4695), rabbit anti-p-ERK1/2 (1:500 ...
• Dysfunctional mechanotransduction regulates the progression of PIK3CA-driven vascular malformations

  Wen Yih Aw, et al., bioRxiv - Bioengineering 2024

  Quote: ... and anti-phospho-myosin light chain 2 (Thr18/Ser19) (1:1000, Cell Signaling Technology, #3674). After overnight incubation with primary antibodies ...
• Rhes, a Striatal Enriched Protein, Regulates Post-Translational Small-Ubiquitin-like-Modifier (SUMO) Modification of Nuclear Proteins and Alters Gene Expression

  Oscar Rivera, et al., bioRxiv - Biochemistry 2020

  Quote: ... #2983), Histone H3 (1:10,000, #4499), MEK1/2 (1:1000, #8727) and LDH (1:5000, #2012;) were from Cell Signaling Technology, Inc ...
• Role of miR-181c in Diet-Induced Obesity Through Regulation of Lipid Synthesis in Liver

  Kei Akiyoshi, et al., bioRxiv - Cell Biology 2021

  Quote: ... the membrane was incubated with antibody that recognizes proteins IDH 1 (1:1000) and IDH 2 (1:1000) (Cell Signaling, MA) and α-Tubulin (Abcam ...
• A critical role of a eubiotic microbiota in gating proper immunocompetence in Arabidopsis

  Bradley C. Paasch, et al., bioRxiv - Plant Biology 2023

  Quote: ... Blots for detecting phosphorylated MAPK were blocked in 5% BSA and immunoblotted with a phosphor-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) antibody (Cell Signaling). Horseradish peroxidase-conjugated anti-rabbit antibody produced in goat (Agrisera ...