Carbamic acid 2 4 hexadienyl 1 1 dimethylethyl ester E E 9cifrom Selleck Chemicals

ITD-1

ITD-1 is a potent TGF-β inhibitor. It does not block the kinase activity of either type I...

Cat# S6713, SKU# S6713-10mM/1mL, 10mM/1mL, $117.00 Ask

HA14-1

HA14-1 is a non-peptidic ligand of a Bcl-2 surface pocket with IC50 of ~9 μM.

Cat# S1071, SKU# S1071-50mg, 50mg, $170.00 Ask

Liproxstatin-1

Liproxstatin-1 is a potent ferroptosis inhibitor with an IC50 of 22 nM.

Cat# S7699, SKU# S7699-100mg, 100mg, $997.00 Ask

Cited in: Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia

Johnson Ung, et al., bioRxiv - Cancer Biology 2023

Quote: ... liproxstatin-1 (Selleck Chemicals, #S7699); ferrostatin-1 (Selleck Chemicals ...

TAPI-1

TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors. TAPI-1 is also...

Cat# S7434, SKU# S7434-1mg, 1mg, $270.00 Ask

Cited in: Targeting neuronal activity-regulated neuroligin-3 dependency for high-grade glioma therapy

Humsa S. Venkatesh, et al., bioRxiv - Neuroscience 2017

Quote: ... TAPI-1 at 20uM (ADAM17 inhibitor; S7434; Selleck Chemicals); GI 254023X at 200nM (ADAM10 inhibitor ...

Torin 1

Torin 1 is a potent inhibitor of mTORC1/2 with IC50 of 2 nM/10 nM in cell-free assays; exhibits...

Cat# S2827, SKU# S2827-10mg, 10mg, $170.00 Ask

Cited in: Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1

Pei-Yun Tsai, et al., bioRxiv - Cancer Biology 2020

Quote: ... Torin 1 (Selleck Chemicals, S2827).

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WQ 1

WQ 1 is a high affinity and selective σ1 receptor antagonist with pKi values of 10.85, 6.53 and...

Cat# E0388, SKU# E0388-5mg, 5mg, $227.00 Ask

AMI-1

AMI-1 is a potent and specific Histone Methyltransferase (HMT) inhibitor with IC50 of 3.0 μM and...

Cat# S7884, SKU# S7884-10mM/1mL, 10mM/1mL, $117.00 Ask

RCM-1

RCM-1 is a nontoxic inhibitor of Forkhead box M1 (FOXM1) that suppresses goblet cell metaplasia...

Cat# S6898, SKU# S6898-25mg, 25mg, $717.00 Ask

BTB-1

BTB-1 is a novel, selective and reversible inhibitor of the mitotic motor protein Kif18A with...

Cat# S6796, SKU# S6796-5mg, 5mg, $97.00 Ask

Stafia-1

Stafia-1 is the first STAT5a inhibitor that inhibits STAT5a (IC50=22.2 μM, Ki=10.9 μM) with at...

Cat# E0485, SKU# E0485-25mg, 25mg, $870.00 Ask

NQDI-1

NQDI 1, an inhibitor of ASK1(apoptosis signal-regulating kinase 1), attenuates acute ischemic...

Cat# S8289, SKU# S8289-50mg, 50mg, $397.00 Ask

Spautin-1

Spautin-1 is a potent and specific autophagy inhibitor, and inhibits the deubiquitinating...

Cat# S7888, SKU# S7888-1g, 1g, $1470.00 Ask

LCS-1

LCS-1 is an inhibitor of superoxide dismutase 1(SOD1) with IC50 of 1.07 μM.

Cat# E2832, SKU# E2832-5mg, 5mg, $70.00 Ask

Necrostatin-1

Necrostatin-1 (Nec-1) is a specific RIP1 (RIPK1) inhibitor and inhibits TNF-α-induced...

Cat# S8037, SKU# S8037-10mg, 10mg, $97.00 Ask

Cited in: Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia

Johnson Ung, et al., bioRxiv - Cancer Biology 2023

Quote: ... necrostatin-1 (Selleck Chemicals, #S8037); pepstatin A (Cayman ...

A2ti-1

A2ti-1 is a selective and high-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t)...

Cat# E1421, SKU# E1421-5mg, 5mg, $297.00 Ask

NGI-1

NGI-1 is an aminobenzamide-sulfonamide compound that targets both oligosaccharyltransferase...

Cat# S8750, SKU# S8750-10mM/1mL, 10mM/1mL, $99.00 Ask

Liproxstatin-1

Liproxstatin-1 is a potent ferroptosis inhibitor with an IC50 of 22 nM.

Cat# S7699, SKU# S7699-5mg, 5mg, $147.00 Ask

Cited in: Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia

Johnson Ung, et al., bioRxiv - Cancer Biology 2023

Quote: ... liproxstatin-1 (Selleck Chemicals, #S7699); ferrostatin-1 (Selleck Chemicals ...

BMS-1

BMS-1 is a small-molecule inhibitor of PD-1/PD-L1 interaction with IC50 of 6 nM.

Cat# S7911, SKU# S7911-10mM/1mL, 10mM/1mL, $167.00 Ask

SC-1

SC-1 (1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea, STAT3-IN-7), a...

Cat# S0986, SKU# S0986-5mg, 5mg, $427.00 Ask

SANT-1

SANT-1 directly binds to Smoothened (Smo) receptor with Kd of 1.2 nM and inhibits Smo agonist...

Cat# S7092, SKU# S7092-10mM/1mL, 10mM/1mL, $157.00 Ask

AMI-1

AMI-1 is a potent and specific Histone Methyltransferase (HMT) inhibitor with IC50 of 3.0 μM and...

Cat# S7884, SKU# S7884-25mg, 25mg, $297.00 Ask

Necrostatin-1

Necrostatin-1 (Nec-1) is a specific RIP1 (RIPK1) inhibitor and inhibits TNF-α-induced...

Cat# S8037, SKU# S8037-100mg, 100mg, $270.00 Ask

Cited in: Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia

Johnson Ung, et al., bioRxiv - Cancer Biology 2023

Quote: ... necrostatin-1 (Selleck Chemicals, #S8037); pepstatin A (Cayman ...

MID-1

MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction,...

Cat# E0794, SKU# E0794-5mg, 5mg, $209.00 Ask

SANT-1

SANT-1 directly binds to Smoothened (Smo) receptor with Kd of 1.2 nM and inhibits Smo agonist...

Cat# S7092, SKU# S7092-50mg, 50mg, $570.00 Ask

ISO-1

ISO-1 (MIF Antagonist) is an inhibitor of MIF (Macrophage migration inhibitory factor)...

Cat# S7732, SKU# S7732-5mg, 5mg, $107.00 Ask

Stafia-1

Stafia-1 is the first STAT5a inhibitor that inhibits STAT5a (IC50=22.2 μM, Ki=10.9 μM) with at...

Cat# E0485, SKU# E0485-5mg, 5mg, $290.00 Ask

3-Amino-4-hydroxybenzoic acid

3-Amino-4-hydroxybenzoic acid is a monohydroxybenzoic acid.

Cat# S6361, SKU# S6361-25mg, 25mg, $97.00 Ask

3-Amino-4-methylpentanoic acid

3-Amino-4-methylpentanoic acid (beta-Leucine, DL-Homovaline, DL-beta-leucine,...

Cat# S6142, SKU# S6142-25mg, 25mg, $107.00 Ask

4-Bromo-3-hydroxybenzoic acid

4-bromo-3-hydroxybenzoic acid is a potent inhibitor of the enzyme histidine decarboxylase with...

Cat# S5444, SKU# S5444-25mg, 25mg, $97.00 Ask

4-Bromo-3-hydroxybenzoic acid

4-bromo-3-hydroxybenzoic acid is a potent inhibitor of the enzyme histidine decarboxylase with...

Cat# S5444, SKU# S5444-1g, 1g, $970.00 Ask

4-Methyl-n-octanoic Acid

4-Methyl-n-octanoic Acid is a flavouring ingredient.

Cat# S6029, SKU# S6029-25ul, 25ul, $97.00 Ask

4-Hydroxy-3-methylbenzoic acid

4-Hydroxy-3-methylbenzoic acid is a normal organic acid identified in urine specimens from a...

Cat# S6297, SKU# S6297-25mg, 25mg, $97.00 Ask

Azetidine-2-carboxylic acid

Azetidine-2-carboxylic acid (L-Aze) is a toxic and teratogenic non-protein amino acid that is...

Cat# S5572, SKU# S5572-25mg, 25mg, $97.00 Ask

D(-)-2-Aminobutyric acid

D(-)-2-Aminobutyric acid is an unnatural amino acid serving as an important intermediate in...

Cat# S6330, SKU# S6330-25mg, 25mg, $97.00 Ask

DL-2-Aminoadipic acid

DL-2-Aminoadipic acid is an excitatory amino acid analogue, which functions as a glutamine...

Cat# S5442, SKU# S5442-25mg, 25mg, $97.00 Ask

Pyrrole-2-carboxylic acid

Pyrrole-2-carboxylic acid (2-Pyrrolecarboxylic acid) is a degradation product of sialic acids...

Cat# S5832, SKU# S5832-25mg, 25mg, $97.00 Ask

Anthraquinone-2-carboxylic Acid

Anthraquinone-2-carboxylic Acid is a novel electron shuttling mediator, showing potent...

Cat# S9359, SKU# S9359-25mg, 25mg, $97.00 Ask

Indole-2-carboxylic acid

Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation.

Cat# S6228, SKU# S6228-25mg, 25mg, $97.00 Ask

(S)-2-Hydroxysuccinic acid

(S)-2-Hydroxysuccinic acid (L-Malic acid) is a naturally occurring isomer of malic acid, found...

Cat# S6292, SKU# S6292-25mg, 25mg, $97.00 Ask

DL-2-Aminoadipic acid

DL-2-Aminoadipic acid is an excitatory amino acid analogue, which functions as a glutamine...

Cat# S5442, SKU# S5442-1g, 1g, $970.00 Ask

Azetidine-2-carboxylic acid

Azetidine-2-carboxylic acid (L-Aze) is a toxic and teratogenic non-protein amino acid that is...

Cat# S5572, SKU# S5572-1g, 1g, $970.00 Ask

N-(2-Acetamido)-2-Iminodiacetic acid

N-(2-Acetamido)-2-Iminodiacetic acid (ADA buffer) is a biological buffer component and can be...

Cat# S6310, SKU# S6310-25mg, 25mg, $97.00 Ask

trans-2-Methyl-2-pentenoic Acid

trans-2-Methyl-2-pentenoic Acid ((E)-2-Methyl-2-pentenoic Acid, strawberry acid) has a sweet...

Cat# S6327, SKU# S6327-25ul, 25ul, $97.00 Ask

1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride (1:1)

1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-Echinocandin B Hydrochloride (Anidulafungin Nucleus) is...

Cat# E0739, SKU# E0739-5mg, 5mg, $129.00 Ask

ERK5-IN-1

ERK5-IN-1 (XMD17-109) is a potent, and selective ERK5 inhibitor with IC50 of 162 nM.

Cat# S7334, SKU# S7334-25mg, 25mg, $477.00 Ask

DDR1-IN-1

DDR1-IN-1 is a potent and selective discoidin domain receptor 1 (DDR1) receptor tyrosine kinase...

Cat# S7498, SKU# S7498-25mg, 25mg, $447.00 Ask

mTOR inhibitor-1

mTOR inhibitor-1 is a novel mTOR pathway inhibitor which can suppress cells proliferation and...

Cat# S0179, SKU# S0179-5mg, 5mg, $257.00 Ask

1-Methoxy PMS

Methoxy-PMS (1-Methoxy PMS), an active oxygen formation inducer, is a stable electron-transport...

Cat# S7770, SKU# S7770-25mg, 25mg, $97.00 Ask

Raf inhibitor 1

Raf inhibitor 1 is a potent Raf kinase inhibitor with Kis of 1 nM, 1 nM, and 0.3 nM for B-Raf...

Cat# E2651, SKU# E2651-5mg, 5mg, $170.00 Ask

1-Naphthyl acetate

1-Naphthyl acetate is usually used in a rapid staining method for identification of macrophages....

Cat# S4804, SKU# S4804-25mg, 25mg, $97.00 Ask

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