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1 - 8 of 8 citations for 6 methyl 2 3 pyridinedicarboxylic acid since 2019

• In Vivo Biorthogonal Antibody Click for Dual Targeting and Augmented Efficacy in Cancer Treatment

  Sandeep Surendra Panikar, et al., bioRxiv - Cancer Biology 2023

  Quote: ... The purified mAbs was then reacted with a 20-fold molar excess of 2-S-(4-Isothiocyanatobenzyl)-1,4,7-triazacyclononane-1,4,7-triacetic acid (p-SCN-Bn-NOTA, Macrocyclics) overnight at 4 °C with gentle agitation ...
• Supramolecular Organization Predicts Protein Nanoparticle Delivery to Neutrophils for Acute Lung Inflammation Diagnosis and Treatment

  Jacob W. Myerson, et al., bioRxiv - Bioengineering 2020

  Quote: Lysozyme-dextran nanogels were prepared for chelation to 111In by conjugation to S-2-(4-Isothiocyanatobenzyl)-1,4,7,10-tetraazacyclododecane tetraacetic acid (p-SCN-Bn-DOTA, Macrocyclics). Nanogels were moved to metal free pH 8.3 1 M NaHCO3 buffer by three-fold centrifugation (16000xg for 15 minutes ...
• CD46 targeted ²¹²Pb alpha particle radioimmunotherapy for prostate cancer treatment

  Jun Li, et al., bioRxiv - Bioengineering 2023

  Quote: YS5 was first conjugated with the bi-functional chelator 2-(4-isothiocyanotobenzyl)-1,4,7,10-tetraaza-1,4,7,10-tetra-(2-carbamoylmethyl)-cyclododecane (TCMC; Macrocyclics, Plano, TX) at the molar ratio of TCMC/YS5 at 10:1 ...
• Bioequivalence Assessment of High-Capacity Polymeric Micelle Nanoformulation of Paclitaxel and Abraxane^® in Rodent and Non-Human Primate Models Using a Stable Isotope Tracer Assay

  Duhyeong Hwang, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... 2-S-(4-isothiocyanatobenzyl)-1,4,7-triazacyclononae,1,4,7-triacetic (p-SCN-Bn-NOTA) acid was purchased from Macrocyclics (Plano, TX). All other materials were purchased either from Fisher Scientific Inc ...
• AML ImmunoPET: ⁶⁴Cu-DOTA-anti-CD33 PET-CT imaging of AML in Xenograft mouse model

  Srideshikan Sargur Madabushi, et al., bioRxiv - Cancer Biology 2019

  Quote: The mouse and humanized anti-human CD33 mAb were conjugated with the metal chelator 1,4,7,10-tetraazacyclododecane-N,N′,N′′,N′′′-tetraacetic acid (NHS-DOTA; Macrocyclics, Dallas, TX) as previously described (12) ...
• Imaging the pharmacokinetics and therapeutic availability of the bispecific CD3xTRP1 antibody in syngeneic mouse tumor models

  Gerwin G.W. Sandker, et al., bioRxiv - Immunology 2023

  Quote: ... BsAbs were conjugated with a 15-fold molar excess of isothiocyanatobenzyl-diethylenetriaminepentaacetic acid (ICT-DTPA, p-SCN-Bn-DTPA, Macrocyclics) in 0.1 M NaHCO3 (pH 9.5) ...
• CD46 targeted ²¹²Pb alpha particle radioimmunotherapy for prostate cancer treatment

  Jun Li, et al., bioRxiv - Bioengineering 2023

  Quote: ... and p-SCN-Bn-TCMC (S-2-(4-Isothiocyanatobenzyl)-1,4,7,10-tetraaza-1,4,7,10-tetra(2-carbamoylmethyl)cyclododecane) (catalog No. B-1005) were purchased from Macrocyclics, Inc ...
• An Inflammatory Clock Predicts Multi-morbidity, Immunosenescence and Cardiovascular Aging in Humans

  Nazish Sayed, et al., bioRxiv - Immunology 2019

  Quote: ... The cells were resuspended in 100 uL PBS buffer containing 2 ug/mL Live-Dead (DOTA-maleimide (Macrocyclics) containing natural-abundance indium) ...