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1 - 8 of 8 citations for 6 4 METHYLPIPERAZIN 1 YL NICOTINONITRILE since 2019

• Pyronaridine Protects Against SARS-CoV-2 in Mouse

  Ana C. Puhl, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: Pyronaridine tetraphosphate [4-[(7-Chloro-2-methoxybenzo[b][1,5]naphthyridin-10-yl)amino]-2,6-bis(1-pyrrolidinylmethyl)phenol phosphate (1:4)] (12) was purchased from BOC Sciences (Shirley NY). The purity of this compound was greater than 95% ...
• Pyronaridine Tetraphosphate Efficacy Against Ebola Virus Infection in Guinea Pig

  Thomas R. Lane, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: Pyronaridine tetraphosphate [4-[(7-Chloro-2-methoxybenzo[b][1,5]naphthyridin-10-yl)amino]-2,6-bis(1-pyrrolidinylmethyl)phenol phosphate (1:4)] (22) was purchased from BOC Sciences (Shirley NY). Favipiravir was purchased from AdooQ Bioscience (Irvine ...
• Repurposing Pyramax® for the Treatment of Ebola Virus Disease: Additivity of the Lysosomotropic Pyronaridine and Non-Lysosomotropic Artesunate

  Thomas R. Lane, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: Pyronaridine tetraphosphate [4-[(7-Chloro-2-methoxybenzo[b][1,5]naphthyridin-10-yl)amino]-2,6-bis(1-pyrrolidinylmethyl)phenol phosphate (1:4)] (12) was purchased from BOC Sciences (Shirley NY). Tilorone was purchased from BOC Sciences ...
• Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine and Pyronaridine: In vitro Activity Against SARS-CoV-2 and Potential Mechanisms

  Ana C. Puhl, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: Pyronaridine tetraphosphate [4-[(7-Chloro-2-methoxybenzo[b][1,5]naphthyridin-10-yl)amino]-2,6-bis(1-pyrrolidinylmethyl)phenol phosphate (1:4)] (Ekins et al., 2015a) was purchased from BOC Sciences (Shirley NY). Tilorone and quinacrine were purchased from Cayman Chemicals (Ann Arbor ...
• Scalable production of tissue-like vascularised liver organoids from human PSCs

  Sean P Harrison, et al., bioRxiv - Cell Biology 2020

  Quote: ... depending on the cell line and 3 or 4 μM CHIR99021 (BOC Sciences). Optimal conditions need to be established for each line based on our previously established protocol 4 ...
• Deep Mutational Scan of a cardiac sodium channel voltage sensor

  Andrew M. Glazer, et al., bioRxiv - Genetics 2019

  Quote: ... and 100 µg/ml brevetoxin A (PbTx-1; BOC Sciences) in DMSO ...
• A Trypanosoma brucei ORFeome-based Gain-of-Function Library identifies genes that promote survival during melarsoprol treatment

  M Carter, et al., bioRxiv - Genetics 2020

  Quote: ... and grown in HMI-9 medium containing Dox (when appropriate) plus melarsoprol at 17 nM or 35 nM melarsoprol (BoC sciences, CAS 494-79-1). Melarsoprol stocks were diluted in DMSO and cultures treated for the indicated duration (Fig ...

  Product cited:

  Melarsoprol

  Cat# 494-79-1, Inquire Ask
• A Trypanosoma brucei ORFeome-based Gain-of-Function Library reveals novel genes associated with melarsoprol resistance

  M Carter, et al., bioRxiv - Genetics 2019

  Quote: ... and grown in HMI-9 medium containing Dox (when appropriate) plus melarsoprol at 17 nM or 35 nM melarsoprol (BoC sciences, CAS 494-79-1). Melarsoprol stocks were diluted in DMSO.

  Product cited:

  Melarsoprol

  Cat# 494-79-1, Inquire Ask