Labshake search

1 - 14 of 14 citations for 6 PHENYL 4 TRIFLUOROMETHYL 2 PYRIDONE since 2019

• High-throughput screening of the ReFRAME, Pandemic Box, and COVID Box drug repurposing libraries against SARS-CoV2 nsp15 endoribonuclease to identify small-molecule inhibitors of viral activity

  Ryan Choi, et al., bioRxiv - Microbiology 2021

  Quote: ... a 4 nucleotide chimeric substrate was commercially synthesized (IDT DNA Inc., Coralville, IA) with a 5’ carboxyfluorescein (FAM ...
• Darwinian properties and their trade-offs in autocatalytic RNA networks

  Sandeep Ameta, et al., bioRxiv - Evolutionary Biology 2019

  Quote: ... DNA/RNA oligonucleotides (Supplementary File 2) were obtained from IDT DNA technologies.
• Computational design of Matrix Metalloprotenaise-9 (MMP-9) resistant to auto-cleavage

  Alessandro Bonadio, et al., bioRxiv - Biochemistry 2023

  Quote: ... Gene blocks of MMP-9Cat variants Des 3 and Des 4 were purchased from IDT DNA, USA ...
• Bacteriophage SP01 Gene Product 56 (gp56) Inhibits Bacillus subtilis Cell Division by Interacting with DivIC/FtsL to Prevent Pbp2B/FtsW Recruitment

  Amit Bhambhani, et al., bioRxiv - Microbiology 2020

  Quote: All plasmids are listed in Table 2 and oligonucleotides purchased from IDT DNA or Fisher used for their construction are listed in Table 3 ...
• Negeviruses reduce replication of alphaviruses during co-infection

  Edward I. Patterson, et al., bioRxiv - Microbiology 2020

  Quote: ... and a domain linker ((G4S)4) between the variable heavy (VH) and variable light (VL) domains (Integrative DNA Technologies) (Figure 1B) ...
• SARS-CoV-2 proteases cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species and the search for reservoir hosts

  Mehdi Moustaqil, et al., bioRxiv - Molecular Biology 2020

  Quote: ... coli C41(DE3) cells were transformed with the SARS-CoV-2 pET-28a-nsp5 plasmid (IDT DNA). Single colonies were used to inoculate LB media supplemented with kanamycin (50 μg/mL) ...
• Frizzled2 receives the WntA morphogen during butterfly wing pattern formation

  Joseph J Hanly, et al., bioRxiv - Developmental Biology 2023

  Quote: ... ordered at the 2 nmol or 10 nmol scales as Custom DsiRNAs with standard purification (IDT DNA Technologies), resuspended at 70-100 μM in 1X Bombyx injection buffer (pH 7.2 ...
• Co-option of Plasmodium falciparum PP1 for egress from host erythrocytes

  Aditya S. Paul, et al., bioRxiv - Microbiology 2020

  Quote: ... The resulting plasmid pLN-PP1-HA3-loxP was further modified to target endogenous pfpp1 with HA3 and loxP by introduction of a 5’ homology region for the gene (HR1, 682 bp of genomic DNA sequence for exons 2 and 3) fused to a recodonized synthetic fragment (IDT DNA) for exons 4 and 5 ...
• The carboxyl-termini of RAN translated GGGGCC nucleotide repeat expansions modulate toxicity in models of ALS/FTD

  Fang He, et al., bioRxiv - Genetics 2020

  Quote: ... The hybridization solution is as follows: 0.6ng/ml Cy5 labeled 2’-O-Me-(CCCCGG)5 RNA probe (IDT DNA Technologies, IA), 0.02% BSA ...
• The P681H mutation in the Spike glycoprotein confers Type I interferon resistance in the SARS-CoV-2 alpha (B.1.1.7) variant

  Maria Jose Lista, et al., bioRxiv - Microbiology 2021

  Quote: ... The relative quantities of envelope (E) gene were measured using SARS-CoV-2 (2019-nCoV) CDC qPCR Probe Assay (IDT DNA technologies). Relative quantities of E gene were normalised to GAPDH mRNA levels (Applied Bioscience ...
• The C-terminal PARP domain of the long ZAP isoform contributes essential effector functions for CpG-directed antiviral activity

  Dorota Kmiec, et al., bioRxiv - Microbiology 2021

  Quote: ... The relative quantity of nucleocapsid (N) RNA was measured using a SARS-CoV-2 (2019-nCoV) CDC qPCR N1 and control RNAseP probe set (IDT DNA Technologies). qPCR reactions were performed in duplicates with Taqman Universal PCR mix (Thermo ...
• The polybasic cleavage site in the SARS-CoV-2 spike modulates viral sensitivity to Type I IFN and IFITM2

  Helena Winstone, et al., bioRxiv - Immunology 2020

  Quote: ... The relative quantities of nucleocapsid (N) gene were measured using SARS-CoV-2 (2019-nCoV) CDC qPCR Probe Assay (IDT DNA technologies).
• The P681H mutation in the Spike glycoprotein escapes IFITM restriction and is necessary for type I interferon resistance in the SARS-CoV-2 alpha variant

  Maria Jose Lista, et al., bioRxiv - Microbiology 2022

  Quote: ... The relative quantities of envelope (E) gene were measured using SARS-CoV-2 (2019-nCoV) CDC qPCR Probe Assay (IDT DNA technologies). Relative quantities of E gene were normalized to GAPDH mRNA levels (Applied Bioscience ...
• LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome

  Alexandra Viktoria Busley, et al., bioRxiv - Cell Biology 2024

  Quote: ... as previously described.10 Genetic correction of the pathological gene variant in the patient-derived iPSC line UMGi137-A clone 2 was performed using ribonucleoprotein-based CRISPR/Cas9 using crRNA/tracrRNA and Hifi SpCas9 (IDT DNA technologies) by targeting exon 15 of the LZTR1 gene ...