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1 - 14 of 14 citations for Reversine since 2019

• CDK4/6 inhibitors induce replication stress to cause long-term cell cycle withdrawal

  Lisa Crozier, et al., bioRxiv - Cancer Biology 2021

  Quote: ... reversine (Sigma, R3904), doxorubicin (Selleckchem ...
• HIF1A contributes to the survival of aneuploid and mosaic pre-implantation embryos

  Estefania Sanchez-Vasquez, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Reversine (Sigma, R3904), AZ3146 (Sigma ...
• A novel human model to deconvolve cell-intrinsic phenotypes of genetically dysregulated pathways in lung squamous cell carcinoma

  Julia Ogden, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Reversine (Sigma-Aldrich, R3904) was added to a final concentration of 2nM in positive control wells to induce caspase activity ...
• CDC20 determines the sensitivity to spindle assembly checkpoint (SAC) inhibitors

  Siqi Zheng, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or 250 nM reversine (R3904; Sigma-Aldrich) on 15 cm dishes (833903 ...
• Aurora kinase A is essential for meiosis in mouse oocytes

  Cecilia S. Blengini, et al., bioRxiv - Cell Biology 2021

  Quote: ... a final concentration of 1 μM reversine (Sigma-Aldrich) was added to the oocytes.
• Opposing motors provide mechanical and functional robustness in the human spindle

  Lila Neahring, Nathan H. Cho, Sophie Dumont, bioRxiv - Cell Biology 2021

  Quote: ... the MPS1 inhibitor reversine (final concentration 500 nM, R3904, Sigma) was added 45 min after STLC ...
• The BUBR1 pseudokinase domain promotes efficient kinetochore PP2A-B56 recruitment to regulate spindle checkpoint silencing and chromosome alignment

  Luciano Gama Braga, et al., bioRxiv - Cell Biology 2019

  Quote: ... and Reversine (Sigma, Cat# R3904-1MG, 1 mM for 30 minutes). Knock-downs were obtained with dsiRNA (IDT ...
• Cancer tolerance to chromosomal instability is driven by Stat1 inactivation in vivo

  Michael Schubert, et al., bioRxiv - Cancer Biology 2021

  Quote: ... the medium was supplemented with 500 nM Reversine (Sigma Aldrich, R3904) or DMSO (AppliChem ...
• The mitotic protein NuMA plays a spindle-independent role in nuclear formation and mechanics

  Andrea Serra-Marques, et al., bioRxiv - Cell Biology 2020

  Quote: ... to depolymerize spindle microtubules and with 320 nM reversine (R3904; Sigma-Aldrich) to inhibit MPS1 and silence the spindle assembly checkpoint (Fig ...
• Selective vulnerability of aneuploid human cancer cells to inhibition of the spindle assembly checkpoint

  Yael Cohen-Sharir, et al., bioRxiv - Cancer Biology 2020

  Quote: ... reversine and mitoxantrone were purchased from Sigma-Aldrich (Saint-Louis, MO, USA, and). Following incubation with the drug ...
• Kinetochore-associated Mps1 regulates the strength of kinetochore-microtubule attachments via Ndc80 phosphorylation

  Krishna K. Sarangapani, et al., bioRxiv - Cell Biology 2021

  Quote: ... 10 μM ATP) containing 66 nM γ-32P-ATP with either 5 µM reversine (Sigma R3904) or vehicle (DMSO ...
• An egg sabotaging mechanism drives non-Mendelian transmission in mice

  Frances E. Clark, et al., bioRxiv - Genetics 2024

  Quote: ... transferred to M2 or M16 media with 0.5 µM Reversine (Sigma-Aldrich, Cat# R39-4-1MG), and matured for an additional 11 hr ...
• Ensemble-level organization of human kinetochores and evidence for distinct tension and attachment sensors

  Emanuele Roscioli, et al., bioRxiv - Cell Biology 2019

  Quote: ... cells were treated with either DMSO or 1 μM taxol-containing media for 15 min and then 1 μM reversine (Sigma)-containing media was added for 120 min (total imaging time was 135 min) ...
• Aurora kinase A is essential for meiosis in mouse oocytes

  Cecilia S. Blengini, et al., bioRxiv - Cell Biology 2021

  Quote: ... Aurka KO oocytes were matured in vitro for 16 h in DMSO or reversine 1μM and were treated with Acidic Tyrode’s solution (Millipore Sigma; MR-004-D) to remove the zona pellucida ...