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1 - 5 of 5 citations for 7 Chloro N 3 chloro 4 fluorophenyl 6 nitro 4 quinazolinamine since 2019

• Identification and Mechanistic Characterization of a Peptide Inhibitor of Glycogen Synthase Kinase (GSK3β) Derived from the Disrupted in Schizophrenia 1 (DISC1) Protein

  Stephanie Saundh, et al., bioRxiv - Neuroscience 2020

  Quote: ... 4) 6X-HisGSK3β purchased from Signalchem (G09-10H-05) for BLI and MST experiments ...
• Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2)

  Apirat Chaikuad, et al., bioRxiv - Biochemistry 2019

  Quote: ... the 5 uL reaction was performed with 4 ug/mL recombinant human ULK2 protein (1-478, SignalChem #U02-11G) and 80 ug/mL MBP in the presence of 25 uM ATP ...
• The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid phosphorylation and inhibits viral infection in vitro

  Tomer M. Yaron, et al., bioRxiv - Microbiology 2020

  Quote: ... All the recombinant kinases (SRPK1/2/3, GSK-3α/β and CK1A/E were obtained from SignalChem.
• MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer

  Olaf Klingbeil, et al., bioRxiv - Cancer Biology 2024

  Quote: ... MARK3 and 14-3-3ε were purchased (Active Motif, 81209, Signalchem, L02-11G, M45-10G, Y75-30H) and purity ...
• Allele-specific activation, enzyme kinetics, and inhibitor sensitivities of EGFR exon 19 deletion mutations in lung cancer

  Benjamin P. Brown, et al., bioRxiv - Cancer Biology 2022

  Quote: ... L747_A750>P (#E10-12MG, lot G1200-3), and L747_E749 (#E10-12LG, lot G1344-5) were purchased from SignalChem. The Promega ADP-Glo™ kinase assay kit was used to quantify the amount of ADP produced by each EGFR variant in 1XBFA buffer and in the presence or absence of erlotinib at varying concentrations ...