(S)-BI 665915
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-12995A |
| CAS # | 1360550-05-5 |
| Pricing | inquire |
| Biological Activity | (S)-BI 665915 is an orally active oxadiazole-containing 5-lipoxygenase-activating protein (FLAP) inhibitor with an IC50 of 1.7 nM for FLAP binding. (S)-BI 665915 inhibits FLAP functional in human whole blood with an IC50 of 45 nM. (S)-BI 665915 demonstrates an excellent cross-species drug metabolism and pharmacokinetics (DMPK) profile and a dose-dependent inhibition of LTB4 production[1]. |
| MWt | 458.52 |
| Formula | C₂₄H₂₆N₈O₂ |