Simvastatin acid ammonium

Supplier MedChemExpress
Product # HY-119695A-5 mg
CAS # 139893-43-9
Pricing 5 mg, USD $50.0
Synonyms Tenivastatin ammonium
MWt 453.61
Formula C₂₅H₄₃NO₆
Biological Activity Simvastatin ammonium is an active metabolite of simvastatin lactone mediated by CYP3A4/5 in the intestinal wall and liver (pKa=5.5). Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene[1].
Purity 99.32%
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