TC-S 7001
TC-S 7001 is a potent and highly selective ROCK inhibitor. Its IC50 values are 0.6 and 1.1 nM for ROCK1 and ROCK2, respectively. It exhibits >200-fold selectivity over TRK and FLT3 receptors, and >900-fold selectivity over a panel of other kinases and cardiovascular relevent enzymes and receptors. It reduces blood pressure in normotensive and hypertensive rats.
Supplier | BOC Sciences |
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Product # | B2693-430574 |
Pricing | 5 mg/unit USD $299 |
Cas | 867017-68-3 |
Molecular Weight | 402.79 |
Molecular Formula | C18H13ClF2N6O |
Canonical SMILES | CC1=CNC2=NC=CC(=C12)OC3=C(C=C(C=C3F)NC4=CC(=NC(=N4)N)Cl)F |