Sodium Lactate
Sodium lactate occurs as a clear, colorless, slightly syrupy liquid. It is odorless, or has a slight odor with a characteristic saline taste. It is hygroscopic.
Supplier | CD Formulation |
---|---|
Product # | PE-0556 |
Pricing | , Inquire for price |
product1 | Stabilizers |
Molecular Formula | C3H5NaO3 |
Molecular Weight | 112.06 |
Applications | Sodium lactate is widely used in cosmetics, food products and pharmaceutical applications including parenteral and topical formulations. Therapeutically, sodium lactate is used in infusions as a component of Ringer-lactate solution; as an alternative for sodium hydrogencarbonate in light acidosis; as a rehydrating agent; and as a carrier for electrolyte concentrates or medicines in perfusion/ infusion solutions. |
Safety | This product is non-toxic and generally recognized as safe, and ADI has not made restrictive regulations. Patients with severe hepatic impairment who cannot convert lactate to bicarbonate should not use it. |
Incompatibilities | This product has a compatibility reaction with novobiocin sodium, oxytetracycline hydrochloride, sodium bicarbonate, calcium sodium edetate, sulfadiazine, etc., and it is forbidden to be compatible with it. |
Synonyms | E325; 2-hydroxypropanoic acid monosodium salt; Lacolin; lactic acid monosodium salt; lactic acid sodium salt; natrii lactatis solutio; Patlac; Purasal; Ritalac NAL; sodium a-hydroxypropionate |
CAS Number | 72-17-3 |
Category | Antimicrobial Preservative; Buffering Agents; Emulsifying Agents; flavoring Agents; Humectant |
UNII | TU7HW0W0QT |
Chemical Name | Sodium lactate |
Grade | Pharmceutical Excipients |
Administration route | Infiltration; Intraperitoneal; Intravenous; Oral; Intracardiac; Intramuscular; Subcutaneous |
Dosage Form | Epidural, IM, IV, and SC injections; oral suspensions; topical gels and solutions |
Stability and Storage Conditions | Sodium lactate should be stored in a well-closed container in a cool, dry, place. Sodium lactate is combustible and decomposes upon heating. |
Commonly used amount and the maximum amount | The maximum dosage for intravenous injection: 50mg; the maximum dosage for general topical preparations: 51.3mg/g. |
Source and Preparation | Add sodium hydroxide to lactic acid under cooling conditions to carry out neutralization reaction, then concentrate in vacuum at 50°C to remove 80% of water, let it stand for about 7 days, and then neutralize with sodium hydroxide, crystallize or not crystallize, so that the content of sodium lactate Get it at 40%~80%. Commercially available products are often made into solutions of a certain concentration. |