| Supplier |
Creative Peptides |
| Product # |
X21210 |
| Pricing |
Inquire
|
| Synonyms |
Nrf2 (74-87); NFE2L2 (74-87)
|
| MolecularWeight |
1631.9
|
| Sequence |
- One Letter Code: LQLDEETGEFLPIQ
- Three Letter Code: H-Leu-Gln-Leu-Asp-Glu-Glu-Thr-Gly-Glu-Phe-Leu-Pro-Ile-Gln-OH
|
| Storage |
-20°C
|
| Explanation |
This peptide is derived from the Neh2 domain of nuclear factor (erythroid-derived 2)-like 2, or Nrf2. Nrf2 is a bZIP transcription factor that regulates the expression of antioxidative and cytoproptective genes. The DxETGE motif of this peptide binds Keap1 Kelch adaptor protein and displaces Nrf2 from Keap1.
|
| Reference |
- 1.Yokota, S. et al. Biochem Pharmacol 81, 289 (2011);
- 2. Lo, S-C. et al. EMBO J 25, 3605 (2006).
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