Integral Membrane Protein 2B (ITM2B) Antibody

Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.

• Supplier: Abbexa Ltd.
• Product #: abx027251-80UL
• Clonality: Polyclonal
• Conjugation: Unconjugated
• Host: Rabbit
• Tested Applications: ELISA, WB, IHC
• UniProt Primary AC: Q9Y287
• Dry Ice: No
• Availability: Shipped within 5-10 working days.
• Note: This product is for research use only.