Rigosertib sodium
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-12037-50 mg |
| CAS # | 592542-60-4 |
| Pricing | 50 mg, USD $290.0 |
| Synonyms | ON-01910 sodium |
| MWt | 473.47 |
| Formula | C₂₁H₂₄NNaO₈S |
| Biological Activity | Rigosertib sodium (ON-01910 sodium) is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3K/Akt pathway, promotes the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle[1][2]. Rigosertib sodium is a selective and non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM[3]. |
| Purity | 99.49% |