Y-27632 2HCl
Y-27632 2HCl is a selective ROCK1 and ROCK2 inhibitor with a Ki of 140 nM and 300nM in a cell-free assay, exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK.
| Supplier | Selleck Chemicals |
|---|---|
| Product # | S1049 |
| Sku # | S1049-10mM/1mL |
| Pricing | 10mM/1mL, $156.00 |
Citations for this product:
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bioRxiv - Cell Biology 2020Quote: ... – 0.1% Y-27632 100 μL/mL (Selleck Chemicals, S1049) – 0.1% DNase (Sigma DN25)].
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bioRxiv - Immunology 2020Quote: ... ROCK-inhibitor (Selleck Chemicals #S1049) and TGFbeta-inhibitor (Selleck Chemicals #S1067 ...
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bioRxiv - Neuroscience 2021Quote: ... 2.5-3 × 106 single cells were added per AggreWell 800 plate well in E8 medium supplemented with the ROCK inhibitor Y27632 (10 μM, Selleck Chemicals, S1049), centrifuged at 100g for 3 minutes and then incubated overnight at 37°C with 5% CO2 ...
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bioRxiv - Immunology 2020Quote: ... 10 μM Rock inhibitor (Selleck Chemicals, S1049), and 1% P/S at 37°C in a 5% CO2 incubator for the first 2 days ...
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bioRxiv - Cell Biology 2020Quote: ... and 10 μM Y-27632 (Selleck Chemicals #S1049).
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bioRxiv - Cell Biology 2021Quote: ... Y-27632 (5 uM, Selleck Chemicals #S1049), SB202190 (500 nM ...
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bioRxiv - Cell Biology 2020Quote: ... with 100μg/mL Y-27632 (Selleck Chemicals, S1049) for single cell dissociation ...
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bioRxiv - Neuroscience 2021Quote: ... and 10 μM ROCK inhibitor (compound Y-27632 2HCl; Selleck Chemicals; Cat. No. S1049). After 24 hours ...
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bioRxiv - Neuroscience 2022Quote: ... containing 10 µM ROCK inhibitor (compound Y-27632 2HCl; Selleck Chemicals; Cat. No. S1049) for 24 hours (this was considered as day 0 in vitro) ...
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bioRxiv - Cancer Biology 2019Quote: ... Y-27632 (cat# S1049) were purchased from Selleck Chemicals (Houston, TX), reconstituted in DMSO ...