Huwentoxin-IV
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-P1220 |
| CAS # | 526224-73-7 |
| Pricing | inquire |
| Biological Activity | Huwentoxin-IV is a potent and selective sodium channel blocker, inhibits neuronal Nav1.7, Nav1.2, Nav1.3 and Nav1.4 with IC50s of 26, 150, 338 and 400 nM, respectively. Huwentoxin-IV preferentially blocks peripheral nerve subtype Nav1.7 by binding neurotoxin receptor site 4. Huwentoxin-IV has analgesic effects on animal models of inflammatory and neuropathic pain[1][2]. |
| MWt | 4106.78 |
| Formula | C₁₇₄H₂₇₈N₅₂O₅₁S₆ |