(Gln22,Asn23)-Amyloid β-Protein (1-40)

(Gln22,Asn23)-Amyloid β-Protein (1-40) is a transgenic mice expressing vasculotropic Dutch/Iowa (E693Q/D694N) mutant human brain Aβ precursor protein (TG-SWDI), which accumulates abundant cerebral microvascular fibrillar amyloid deposition and exhibits strong neuroinflammation. In vitro, double-mutated Aβ peptides showed a tendency to increase fibrillation and pathogenicity compared with Dutch and Iowa single mutants.
Supplier BOC Sciences
Product # BAT-014663
Pricing Inquire
Cas 374796-75-5
Molecular Weight 4327.82
Molecular Formula C194H297N55O56S
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