(Gln22,Asn23)-Amyloid β-Protein (1-40)
(Gln22,Asn23)-Amyloid β-Protein (1-40) is a transgenic mice expressing vasculotropic Dutch/Iowa (E693Q/D694N) mutant human brain Aβ precursor protein (TG-SWDI), which accumulates abundant cerebral microvascular fibrillar amyloid deposition and exhibits strong neuroinflammation. In vitro, double-mutated Aβ peptides showed a tendency to increase fibrillation and pathogenicity compared with Dutch and Iowa single mutants.
Supplier | BOC Sciences |
---|---|
Product # | BAT-014663 |
Pricing | Inquire |
Cas | 374796-75-5 |
Molecular Weight | 4327.82 |
Molecular Formula | C194H297N55O56S |