Myc Proto-Oncogene Protein (MYC) Antibody
MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of the gene encoding MYC have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Supplier | Abbexa Ltd. |
---|---|
Product # | abx031252-400UL |
Pricing | 400 µl USD $601.75 |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Host | Rabbit |
Tested Applications | ELISA, WB, FCM |
UniProt Primary AC | P01106 |
Dry Ice | No |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |