PRMT5-IN-1
PRMT5 IN-1 is a covalent inhibitor of protein arginine methyltransferase 5 (PRMT5) with an IC50 of 11 nM against PRMT5/MEP50. It can be converted into aldehydes and react with C449 to form covalent adducts under physiological conditions.
| Supplier | BOC Sciences |
|---|---|
| Product # | 2366149-83-7 |
| Pricing | Inquire |
| Cas | 2366149-83-7 |
| Molecular Weight | 418.83 |
| Molecular Formula | C19H19ClN4O5 |
| Canonical SMILES | C1C(N2C=NC3=C(C2=N1)C=CN3C4C(C(C(O4)C(C5=CC=C(C=C5)Cl)O)O)O)O |