TC ASK 10

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TC ASK 10 is a potent and orally bioactive ASK1 inhibitor (IC50 = 14 nM) with selectivity for ASK1 over other kinases including ASK2 (IC50 = 0.51 μM), MEKK1, TAK1, IKKβ, ERK1, JNK1, p38α, GSK-3β, PKCθ and B-raf (IC50 > 10 μM). TC ASK 10 blocks downstream JNK1/p38 phosphorylation in cells.

Supplier	BOC Sciences
Product #	1005775-56-3
Pricing	Inquire
Cas	1005775-56-3
Molecular Weight	432.35
Molecular Formula	C21H21N5O.2HCl
Canonical SMILES	CC(C)(C)C1=CC=C(C=C1)C(=O)NC2=CN3C=C(C=CC3=N2)N4C=CN=C4.Cl.Cl

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