Magic™ Membrane Protein Mouse HTR1A (5-hydroxytryptamine (serotonin) receptor 1A)

The 5-HT1A (5-HydroxyTryptamine Receptor 1A) receptor is a subtype of serotonin (5- hydroxytryptamin) receptor located in presynaptic and postsynaptic regions. This receptor plays a role in the regulation of dopamine and serotonin levels in the brain, and thereby affects neural activity, mood and behavior. The 5-HT1A receptors are G-protein coupled receptors that exert their effects through Gi/o proteins to inhibit adenylyl cyclase, as well as other second messenger cascades such as MAPK pathway. The activation of this receptor has been involved in the mechanism of action of anxiolytic, antidepressant and antipsychotic medications.

• Supplier: Creative Biolabs
• Product #: MP0018F