PF-573228

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PF-573228 is an ATP-competitive inhibitor of FAK with IC50 of 4 nM in a cell-free assay, ~50- to 250-fold selective for FAK than Pyk2, CDK1/7 and GSK-3β. PF-573228 induces apoptosis.

Supplier	Selleck Chemicals
Product #	S2013
Sku #	S2013-10mM/1mL
Pricing	10mM/1mL, $190.00

Citations for this product:

Non-catalytic role of phosphoinositide 3-kinase in mesenchymal cell migration through non-canonical induction of p85β/AP-2-mediated endocytosis

Hideaki T. Matsubayashi, et al., bioRxiv - Cell Biology 2023

Quote: ... FAK inhibitor PF-573228 was purchased from Selleck Chemicals (S2013), prepared as 20 mM stock in DMSO ...

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