Forodesine hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-16209-1 mg |
| CAS # | 284490-13-7 |
| Pricing | 1 mg, USD $216.0 |
| Synonyms | BCX-1777 hydrochloride; Immucillin-H hydrochloride |
| MWt | 302.71 |
| Formula | C₁₁H₁₅ClN₄O₄ |
| Biological Activity | Forodesine hydrochloride (BCX-1777 hydrochloride) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine hydrochloride is a potent human lymphocyte proliferation inhibitor. Forodesine hydrochloride could induce apoptosis in leukemic cells by increasing the dGTP levels[1][2]. |
| Purity | 99.86% |