Bumetanide
Supplier | MedChemExpress |
---|---|
Product # | HY-17468-10 mM * 1 mL |
CAS # | 28395-03-1 |
Pricing | 10 mM * 1 mL, USD $72.0 |
Synonyms | Ro 10-6338; PF 1593 |
MWt | 364.42 |
Formula | C₁₇H₂₀N₂O₅S |
Biological Activity | Bumetanide (Ro 10-6338; PF 1593), a highly potent loop diuretic, is a Na+-K+-Cl+ cotransporter (NKCC) blocker. Bumetanide is a selective NKCC1 inhibitor, but also inhibits NKCC2, with IC50s of 0.68 μM and 4.0 μM for hNKCC1A and hNKCC2A, respectively[1][2]. |
Purity | 99.91% |