Hydroxypropyl-β-cyclodextrin
Hydroxypropyl betadex occurs as a white or almost white, amorphous or crystalline powder
| Supplier | CD Formulation |
|---|---|
| Product # | PE-0590 |
| Pricing | , Inquire for price |
| product1 | Stabilizers |
| Molecular Formula | C42H70-XO35RX |
| Molecular Weight | 1135+58X (X is the degree of substitution) |
| Applications | It is applied in medicine, food and environmental protection, especially as drug excipients, which can improve the water solubility and stability of drugs. It can promote the dissolution of weakly polar organic compounds in water. |
| Safety | Compared with other derivatives, the hemolysis sequence was DM-B-CD>SBE1-B-CD≈ 1>SBE4-B-CD>SBE7-B-CD |
| Incompatibilities | The presence of cyclodextrin in aqueous solution may reduce the activity of some antibacterial preservatives. |
| Synonyms | beta-Cyclodextrin 2-hydroxypropyl ethers; HPBCD; HPCD; 2-hydroxypropyl-beta-cyclodextrin; (2-hydroxypropyl)-beta-cyclodextrin; HYDROXYPROPYL-β-CYCLODEXTRIN; beta-Cyclodextrin, 2-hydroxypropyl ether |
| CAS Number | 94035-02-6 |
| Category | Solubilizing Agents; Stabilizing Agents |
| UNII | 1I96OHX6EK |
| Chemical Name | 2-O- (2-hydroxypropyl) -beta-cyclodextrin; 6-O- (2-hydroxypropyl) -beta-cyclodextrin; 2, 6-di-o - (2-hydroxypropyl) -beta-cyclodextrin |
| Grade | Pharmceutical Excipients |
| Administration route | Injection, oral, eye, nose, rectum, and skin |
| Dosage Form | Injection administration, oral preparations, eye, nose, rectum, and skin administration |
| Stability and Storage Conditions | Keep out of light and in airtight storage. |
| Source and Preparation | Hydroxypropyl betacyclodextrin (HP-B-CD) is a hydrophilic derivative of B-CD condensed with 1, 2- propylene oxide. |