SB-277011 hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10847B-10 mg |
| CAS # | 215804-67-4 |
| Pricing | 10 mg, USD $160.0 |
| Synonyms | SB-277011A hydrochloride |
| MWt | 475.02 |
| Formula | C₂₈H₃₁ClN₄O |
| Biological Activity | SB-277011 hydrochloride (SB-277011A hydrochloride) is a potent, selective, orally bioavailable and brain penetrate dopamine D3 receptor (D3R) antagonist with Ki values of 10.7 nM and 11.2 nM at rodent and human D3R, respectively. SB-277011 hydrochloride displays 80- to 100-fold selectivity over other dopamine receptors with pKis of 8.0, 6.0, <5.2, and 5.9 for D3, D2, 5-HT1B, and 5-HT1D receptors, respectively[1][2]. |
| Purity | 98.22% |