Cereblon modulator 1
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-130800-25 mg |
| CAS # | 1860875-51-9 |
| Pricing | 25 mg, USD $330.0 |
| Biological Activity | Cereblon modulator 1 (compound F) is a cereblon (CRBN) E3 ligase modulator. Cereblon modulator 1 specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex. This leads to the ubiquitination of certain substrate proteins and induces the proteasome-mediated degradation of certain transcription factors, including Ikaros (IKZF1) and Aiolos (IKZF3)[1][2]. |
| Purity | 99.51% |
| MWt | 461.85 |
| Formula | C₂₂H₁₈ClF₂N₃O₄ |