PIM1-IN-1
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-111552 |
| CAS # | 1417630-95-5 |
| Pricing | inquire |
| Biological Activity | PIM1-IN-1 is a potent and highly selective PIM1/3 inhibitor, with IC50s of 7, 5530 and 70 nM for PIM1, PIM2, and PIM3, respectively, inhibits the phosphorylation of BAD, a downstream target of PIM, with an EC50 of 262 nM. PIM1-IN-1 shows no obvious effect on FLT3 or hERG binding. Antiproliferative and anti-cancer activity[1]. |
| MWt | 474.56 |
| Formula | C₂₅H₃₀N₈O₂ |