Marizomib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10985-100 μg |
| CAS # | 437742-34-2 |
| Pricing | 100 μg, USD $150.0 |
| Synonyms | Salinosporamide A; NPI-0052 |
| MWt | 313.78 |
| Formula | C₁₅H₂₀ClNO₄ |
| Biological Activity | Marizomib (Salinosporamide A) is a second-generation, irreversible, brain-penetrant, pan-proteasome inhibitor. Marizomib inhibits the CT-L (β5), CT-T-laspase-like (C-L, β1) and trypsin-like (T-L, β2) activities of the 20S proteasome (IC50=3.5, 28, and 430 nM, respectively)[1][2][3]. |
| Purity | ≥98.0% |