Paclitaxel (Taxol, Yewtaxan, Plaxicel, Paxceed, Abraxane, Ebetaxel, Capxol, Paxene, Genetaxyl, Plaxicel, Genexol, Mitotax, Onxol, Nov-Onxol, CAS 33069-62-4), >99.5%
LC Laboratories' Product Number P-9600 - Paclitaxel (Taxol, Yewtaxan, Plaxicel, Paxceed, Abraxane, Ebetaxel, Capxol, Paxene, Genetaxyl, Plaxicel, Genexol, Mitotax, Onxol, Nov-Onxol, CAS 33069-62-4), >99.5% - for research use only. Antitumor and antileukemic agent isolated from the bark of the yew tree, Taxus brevifolia. Binds to β-tubulin and promotes the assembly of microtubules that resist depolymerization preventing normal cell division. Induces apoptosis through a JNK-dependent pathway in the early phase followed by a JNK-independent pathway that results in Bcl-2 phosphorylation.
Supplier | LC Laboratories |
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Product # | P-9600 |
Sku # | P-9600_2g |
Pricing | 2 g, $273.00 |
Citations for this product:
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bioRxiv - Cell Biology 2021Quote: ... with 10 µM taxol (LC Labs, P-9600) and 0.1% DMSO (Fisher ...
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bioRxiv - Cancer Biology 2020Quote: ... Paclitaxel (LC Labs, P-9600), Docetaxel (Sigma-Aldrich ...
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bioRxiv - Biophysics 2022Quote: The microtubules were polymerized with 1 mM GTP for 30 min at 37°C and then stabilized with 20 μM paclitaxel (P-9600; LC Laboratories). Immediately before use ...