Conoidin A
Peroxiredoxins are a ubiquitous family of antioxidant enzymes that also control cytokine-induced peroxide levels and thereby mediate signal transduction in mammalian cells. Conoidin A inactivates peroxiredoxins by covalently binding to the catalytic cysteine on the enzyme. It has been shown to inhibit peroxiredoxin II (IC50 = 23 µM) in the parasite T. gondii and peroxiredoxin I in the hookworm A. ceylanicum.
| Supplier | BOC Sciences |
|---|---|
| Product # | 18080-67-6 |
| Pricing | Inquire |
| Cas | 18080-67-6 |
| Molecular Weight | 348 |
| Molecular Formula | C10H8Br2N2O2 |
| Canonical SMILES | C1=CC=C2C(=C1)N(C(=C([N+]2=O)CBr)CBr)[O-] |