SPT Imidazopyridine 1
SPT Imidazopyridine 1 is a potent serine palmitoyl transferase (SPT) inhibitor (IC50 = 5 nM) used for the treatment of type 2 diabetes and dyslipidemia. SPT Imidazopyridine 1 inhibits incorporation of 14C-serine into ceramide in dose manner, and lowers plasma ceramide levels in vivo. It also has the effect of increasing plasma HDL and reducing VLDL cholesterol levels in rats.
Supplier | BOC Sciences |
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Product # | 1933533-18-6 |
Pricing | Inquire |
Cas | 1933533-18-6 |
Molecular Weight | 364.44 |
Molecular Formula | C22H24N2O3 |
Canonical SMILES | CCCCCCC(=O)C1=CN2C=CN=C2C(=C1)C3=CC=C(C=C3)CC(=O)O |