SPT Imidazopyridine 1

SPT Imidazopyridine 1 is a potent serine palmitoyl transferase (SPT) inhibitor (IC50 = 5 nM) used for the treatment of type 2 diabetes and dyslipidemia. SPT Imidazopyridine 1 inhibits incorporation of 14C-serine into ceramide in dose manner, and lowers plasma ceramide levels in vivo. It also has the effect of increasing plasma HDL and reducing VLDL cholesterol levels in rats.
Supplier BOC Sciences
Product # 1933533-18-6
Pricing Inquire
Cas 1933533-18-6
Molecular Weight 364.44
Molecular Formula C22H24N2O3
Canonical SMILES CCCCCCC(=O)C1=CN2C=CN=C2C(=C1)C3=CC=C(C=C3)CC(=O)O
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