Aldolase A, human recombinant
Fructose bisphosphate aldolase A, also known as Aldolase A is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. It is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Deficiency has been associated with myopathy and hemolytic anemia. Recombinant human Aldolase A, fused to His-tag at N-terminus, was expressed in E. Coliand purified by using conventional chromatography techniques.
| Supplier | CD BioSciences |
|---|---|
| Product # | APE-001 |
| Pricing | 100 μg, Inquire |
| Product Category | Proteins/Enzymes |
| Gene ID | 226 |
| Alternate Name | Fructose bisphosphate Aldolase A, ALDOA, ALDA, GSD12 |
| Molecular Weight | 41.5 kDa |
| Appearance | Liquid |
| Storage Conditions | -80°C |
| Gene Symbol | ALDOA |
| Source | E. coli |
| Physical Form Description | 1 mg/Ll in 20 mM Tris-HCl buffer (pH 8.0) containing 100 mM NaCl and 10% glycerol. |
| Purity by SDS-PAGE | ≥95% |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MPYQYPALTP EQKKELSDIA HRIVAPGKGI LAADESTGSI AKRLQSIGTE NTEENRRFYR QLLLTADDRV NPCIGGVILF HETLYQKADD GRPFPQVIKS KGGVVGIKVD KGVVPLAGTN GETTTQGLDG LSERCAQYKK DGADFAKWRC VLKIGEHTPS ALAIMENANV LARYASICQQ NGIVPIVEPE ILPDGDHDLK RCQYVTEKVL AA |