Recombinant Human Anti-TSHR Antibody (M22)
Recombinant Human Antibody (M22) is capable of binding to TSHR, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-TSHR mAb and CH1-3 region of human IgG and a light chain (LC) encoding VL from anti- TSHR proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. A human monoclonal autoantibody to the TSHR (M22), which is a powerful thyroid stimulator with high affinity for the receptor, and determined its crystal structure at 1.65A° resolution.
| Supplier | Creative Biolabs |
|---|---|
| Product # | PABW-172 |
| Pricing | Inquiry |
| Host | Human |
| Target | TSHR |
| Species Reactivity | Human |
| Type | IgG |
| Applications | WB, ELISA, PK |
| Storage | Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples. |