TAK-659 hydrochloride

Supplier MedChemExpress
Product # HY-100867A-25 mg
CAS # 1952251-28-3
Pricing 25 mg, USD $390.0
Biological Activity TAK-659 hydrochloride is a highly potent, selective, reversible and orally available dual inhibitor of spleen tyrosine kinase (SYK) and fms related tyrosine kinase 3 (FLT3), with an IC50 of 3.2 nM and 4.6 nM for SYK and FLT3, respectively. TAK-659 hydrochloride induces cell death in tumor cells but not in nontumor cells, and with potential for the treatment of chronic lymphocytic leukemia (CLL)[1][2][3][4].
Purity 99.69%
MWt 380.85
Formula C₁₇H₂₂ClFN₆O
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