Indirubin-3'-monoxime
Supplier | MedChemExpress |
---|---|
Product # | HY-19807-50 mg |
CAS # | 160807-49-8 |
Pricing | 50 mg, USD $528.0 |
Synonyms | Indirubin-3'-oxime |
MWt | 277.28 |
Formula | C₁₆H₁₁N₃O₂ |
Biological Activity | Indirubin-3'-monoxime is a potent GSK-3β inhibitor, and weakly inhibits 5-Lipoxygenase, with IC50s of 22 nM and 7.8-10 µM, respectively; Indirubin-3'-monoxime also shows inhibitory activities against CDK5/p25 and CDK1/cyclin B, with IC50s of 100 and 180 nM. |
Purity | 99.95% |