Afuco™ Anti-Human Ferritin ADCC Therapeutic Antibody (AMB8LK), ADCC Enhanced
Anti-Ferritin ADCC Enhanced Antibody (AMB8LK) is an ADCC enhanced antibody produced by our Afuco™ platform. AMB8LK is a chimeric monoclonal antibody specifically recognizing H-ferritin, using for pancreatic cancer, hepatocarcinomas and neuroblastomas. Preclinical studies showed that the immunoconjugate with 90Y has 98% stability over 7 days. The DTPA-AMB8LK has a high reactivity with ferritin. The results of the biodistribution in CAPAN-1 tumor-bearing nude mice at 120 hours after injection of 90Y-labelled AMB8LK are showed a high preferential distribution at the tumor site.
| Supplier | Creative Biolabs |
|---|---|
| Product # | AFC-263CL |
| Pricing | Inquiry |
| Host | Chimeric |
| Target | Ferritin |
| Species Reactivity | Human |
| Type | ADCC enhanced antibody |
| Storage | Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |