Immortalized Mouse Cerebellar Capillary Endothelial Cells (cerebEND)
Immortalized Mouse Cerebellar Capillary Endothelial Cells (cerebEND) from Ace Therapeutics is a specialized cell line developed by immortalizing primary cells using oncoprotein of murine Polyomavirus, Polyoma middle T antigen (PymT). These cell lines share principal features of the BBB in vivo, retaining the endothelial markers VE-Cadherin and PECAM-1, displaying tight junction-associated markers such as occludin, claudin-3, -5, -12, expressing the BBB marker protein Glut-1 and showing high electrical resistance, representing barrier properties. Immortalized Mouse Cerebral Capillary Endothelial Cells (cEND) can serve as a useful model for studies involving the differentiation and regulation of BBB. Immortalized Mouse Cerebral Capillary Endothelial Cells (cEND) and Immortalized Mouse Cerebral Capillary Endothelial Cells (cEND) together represent important model systems for these different brain regions. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | BBM-C-159 |
| Pricing | Inquiry |
| Product Category | Immortalized Cells |
| Species | Mouse |
| Citation Guidance | If you use our product in a scientific publication, please cite it as "Ace Therapeutics Cat.#". Click here to submit your paper's PubMed ID (PMID) to receive rewards. |
| Source | Brain |
| Recommended Medium | It is recommended to use Immortalized Mouse Cerebellar Capillary Endothelial Cells (cerebEND) Medium Kit for culturing in vitro. |
| Cell Type | Endothelial |
| Disease | Normal |
| Quality Control | Immortalized Mouse Cerebellar Capillary Endothelial Cells (cerebEND) test negative for bacteria, yeast, fungi, and mycoplasma. |
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