Ipatasertib HCl
Ipatasertib, also known as GDC-0068, is a highly selective pan-Akt inhibitor targeting Akt1/2/3 (IC50= 5 nM/18 nM/8 nM in cell-free assays) with 620-fold selectivity over PKA. Ipatasertib is advancing in clinical development including a Phase 3 trial in patients with prostate cancer and three Phase 2 trials in patients with breast cancer, gastric cancer and prostate cancer.
| Supplier | BOC Sciences |
|---|---|
| Product # | 1489263-16-2 |
| Pricing | Inquire |
| Cas | 1489263-16-2 |
| Molecular Weight | 494.46 |
| Molecular Formula | C24H33Cl2N5O2 |
| Canonical SMILES | O=C(N1CCN(C2=C([C@H](C)C[C@H]3O)C3=NC=N2)CC1)[C@@H](C4=CC=C(Cl)C=C4)CNC(C)C.[H]Cl |