β-Naphthoflavone-CH2-OH
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-130269 |
| Pricing | inquire |
| Biological Activity | β-Naphthoflavone-CH2-OH (β-NF-CH2-OH) is a ligand for arylhydrocarbon receptor (AhR) E3 ligase. β-Naphthoflavone-CH2-OH can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs (e.g., β-naphthoflavone-JQ1) that recruit the AhR E3 ligase complex by incorporating AhR ligands into chimeric molecules. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins [1]. |
| Synonyms | β-NF-CH2-OH |
| MWt | 302.32 |
| Formula | C₂₀H₁₄O₃ |