1-(6-Nitro-3-pyridyl)piperazine
1-(6-Nitro-3-pyridyl)piperazine (CAS# 775288-71-6) is a reagent used in the preparation of highly potent and orally bioavailable 4-Thiazol-N-(pyridin-2-yl)pyrimidin-2-amine cyclin-dependant kinases as anticancer agents. Also is an impurity of Palbociclib (P139900), an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
| Supplier | BOC Sciences |
|---|---|
| Product # | BB035974 |
| Pricing | Inquire |
| Cas | 775288-71-6 |
| Molecular Weight | 208.22 |
| Molecular Formula | C9H12N4O2 |
| Canonical SMILES | C1CN(CCN1)C2=CN=C(C=C2)[N+](=O)[O-] |