2'-O-4'-C-Locked-m7GMP Ammonium salt

2'-O-4'-C-Locked-m7GMP Ammonium salt is a modified derivative of guanosine monophosphate (GMP) where a locked nucleic acid (LNA) modification is incorporated at the 2' position and a 4'-carbon linkage (4'-C) is present, along with a 7-methylguanosine (m7G) cap. The locked nucleic acid modification enhances the stability and hybridization affinity of the compound, making it valuable in biochemical applications, especially in RNA research. The inclusion of an ammonium salt further improves its solubility and stability, particularly in aqueous solutions. This modified nucleotide is commonly used in various molecular biology techniques, such as enzymatic reactions, RNA capping studies, and investigations into mRNA processing and translation mechanisms. Its structure closely resembles that of eukaryotic mRNA caps, making it a useful tool for studying mRNA-related processes in biological systems.

• Supplier: BOC Sciences
• Product #: BRP-00670
• Molecular Weight: 389.26 (free acid)
• Molecular Formula: C12H16N5O8P (free acid)