Recombinant Human Anti-HIV-1 gp120 Antibody (PGT121)
Recombinant Human Antibody (PGT121) is capable of binding to HIV-1 gp120, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-HIV-1 gp120 mAb and CH1-3 region of human IgG and a light chain (LC) encoding VL from anti-HIV-1 gp120 proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. Although PGT121 binds complex-type N-glycans, PGT121 recognized high-mannose-only HIV envelopes in isolation and on virions.
| Supplier | Creative Biolabs |
|---|---|
| Product # | PABZ-203 |
| Pricing | Inquiry |
| Host | Human |
| Target | HIV-1 gp120 |
| Species Reactivity | HIV-1 |
| Type | IgG |
| Applications | Can be useful in applications such as: Neutralization, Enzyme-linked Immunosorbent Assay |
| Storage | Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples. |