FKBP12 PROTAC dTAG-13

Supplier MedChemExpress
Product # HY-114421-1 mg
CAS # 2064175-41-1
Pricing 1 mg, USD $550.0
Synonyms dTAG-13
MWt 1049.17
Formula C₅₇H₆₈N₄O₁₅
Biological Activity FKBP12 PROTAC dTAG-13 (dTAG-13) is a PROTAC-based heterobifunctional degrader. FKBP12 PROTAC dTAG-13 (dTAG-13) is a degrader of FKBP12F36V with expression of FKBP12F36V in-frame with a protein of interest. FKBP12 PROTAC dTAG-13 (dTAG-13) also is a selective degrader of BET bromodomain transcriptional co-activator BRD4 by bridging BET bromodomains to an E3 ubiquitin ligase CRBN[1].
Purity ≥98.0%
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