FKBP12 PROTAC dTAG-13
Supplier | MedChemExpress |
---|---|
Product # | HY-114421-1 mg |
CAS # | 2064175-41-1 |
Pricing | 1 mg, USD $550.0 |
Synonyms | dTAG-13 |
MWt | 1049.17 |
Formula | C₅₇H₆₈N₄O₁₅ |
Biological Activity | FKBP12 PROTAC dTAG-13 (dTAG-13) is a PROTAC-based heterobifunctional degrader. FKBP12 PROTAC dTAG-13 (dTAG-13) is a degrader of FKBP12F36V with expression of FKBP12F36V in-frame with a protein of interest. FKBP12 PROTAC dTAG-13 (dTAG-13) also is a selective degrader of BET bromodomain transcriptional co-activator BRD4 by bridging BET bromodomains to an E3 ubiquitin ligase CRBN[1]. |
Purity | ≥98.0% |